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Challenges and recommendations for the translation of biomarkers of aging.
Biomarkers of Aging Consortium; Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN. Biomarkers of Aging Consortium, et al. Among authors: herzog cms. Nat Aging. 2024 Oct;4(10):1372-1383. doi: 10.1038/s43587-024-00683-3. Epub 2024 Sep 16. Nat Aging. 2024. PMID: 39285015 Review.
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
Validation of biomarkers of aging.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. Moqri M, et al. Nat Med. 2024 Feb;30(2):360-372. doi: 10.1038/s41591-023-02784-9. Epub 2024 Feb 14. Nat Med. 2024. PMID: 38355974 Free PMC article. Review.
The DNA methylome of cervical cells can predict the presence of ovarian cancer.
Barrett JE, Jones A, Evans I, Reisel D, Herzog C, Chindera K, Kristiansen M, Leavy OC, Manchanda R, Bjørge L, Zikan M, Cibula D, Widschwendter M. Barrett JE, et al. Nat Commun. 2022 Feb 1;13(1):448. doi: 10.1038/s41467-021-26615-y. Nat Commun. 2022. PMID: 35105887 Free PMC article.
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.
Barrett JE, Herzog C, Jones A, Leavy OC, Evans I, Knapp S, Reisel D, Nazarenko T, Kim YN, Franchi D, Ryan A, Franks J, Bjørge L, Zikan M, Cibula D, Harbeck N, Colombo N, Dudbridge F, Jones L, Sundström K, Dillner J, Rådestad AF, Gemzell-Danielsson K, Pashayan N, Widschwendter M. Barrett JE, et al. Nat Commun. 2022 Feb 1;13(1):449. doi: 10.1038/s41467-021-27918-w. Nat Commun. 2022. PMID: 35105882 Free PMC article.
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