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Page 1
Lenacapavir Exhibits Atropisomerism-Mechanistic Pharmacokinetics and Disposition Studies of Lenacapavir Reveal Intestinal Excretion as a Major Clearance Pathway.
Zheng J, Lu B, Carr G, Mwangi J, Wang K, Hao J, Staiger KM, Kozon N, Murray BP, Bashir M, Gohdes MA, Tse WC, Schroeder S, Graupe M, Link JO, Yoon J, Chiu A, Rowe W, Smith BJ, Subramanian R. Zheng J, et al. Among authors: graupe m. J Pharmacol Exp Ther. 2024 Sep 18;391(1):91-103. doi: 10.1124/jpet.124.002302. J Pharmacol Exp Ther. 2024. PMID: 39117460
Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion.
Weber E, Subramanian R, Rowe W, Graupe M, Ling J, Shen G, Begley R, Sager J, Wolckenhauer S, Rhee M, Palaparthy R, Singh R. Weber E, et al. Among authors: graupe m. Clin Pharmacokinet. 2024 Feb;63(2):241-253. doi: 10.1007/s40262-023-01328-1. Epub 2024 Jan 18. Clin Pharmacokinet. 2024. PMID: 38236562
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro.
Rossi M, Vecchi A, Tiezzi C, Barili V, Fisicaro P, Penna A, Montali I, Daffis S, Fletcher SP, Gaggar A, Medley J, Graupe M, Lad L, Loglio A, Soffredini R, Borghi M, Pollicino T, Musolino C, Alfieri A, Brillo F, Laccabue D, Massari M, Boarini C, Abbati G, Pedrazzi G, Missale G, Lampertico P, Ferrari C, Boni C. Rossi M, et al. Among authors: graupe m. Gut. 2023 Nov;72(11):2123-2137. doi: 10.1136/gutjnl-2022-327202. Epub 2023 Jan 30. Gut. 2023. PMID: 36717219 Free PMC article.
Paediatric acute care cardiology collaborative data registry validation.
Khadr L, Hart SA, Schachtner S, Graupe M, Veneziale KL, Bushnell J, Roberts F, Jolly-Passerini H, Madsen N. Khadr L, et al. Among authors: graupe m. Cardiol Young. 2022 Nov;32(11):1814-1819. doi: 10.1017/S1047951121005047. Epub 2022 Feb 23. Cardiol Young. 2022. PMID: 35193717
Successful Reduction of Postoperative Chest Tube Duration and Length of Stay After Congenital Heart Surgery: A Multicenter Collaborative Improvement Project.
Bates KE, Connelly C, Khadr L, Graupe M, Hlavacek AM, Morell E, Pasquali SK, Russell JL, Schachtner SK, Strohacker C, Tanel RE, Ware AL, Wooton S, Madsen NL, Kipps AK. Bates KE, et al. Among authors: graupe m. J Am Heart Assoc. 2021 Nov 2;10(21):e020730. doi: 10.1161/JAHA.121.020730. Epub 2021 Oct 29. J Am Heart Assoc. 2021. PMID: 34713712 Free PMC article.
High Acuity Therapy Variation Across Pediatric Acute Care Cardiology Units: Results from the Pediatric Acute Care Cardiology Collaborative Hospital Surveys.
Harahsheh AS, Kipps AK, Hart SA, Cassidy SC, Clabby ML, Hlavacek AM, Hoerst AK, Graupe MA, Madsen NL, Bakar AM, Del Grippo EL, Patel SS, Bost JE, Tanel RE; Pediatric Acute Care Cardiology Collaborative (PAC3). Harahsheh AS, et al. Among authors: graupe ma. Pediatr Cardiol. 2021 Jun;42(5):1074-1081. doi: 10.1007/s00246-021-02584-3. Epub 2021 Apr 4. Pediatr Cardiol. 2021. PMID: 33813599 Free PMC article.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Link JO, Rhee MS, Tse WC, Zheng J, Somoza JR, Rowe W, Begley R, Chiu A, Mulato A, Hansen D, Singer E, Tsai LK, Bam RA, Chou CH, Canales E, Brizgys G, Zhang JR, Li J, Graupe M, Morganelli P, Liu Q, Wu Q, Halcomb RL, Saito RD, Schroeder SD, Lazerwith SE, Bondy S, Jin D, Hung M, Novikov N, Liu X, Villaseñor AG, Cannizzaro CE, Hu EY, Anderson RL, Appleby TC, Lu B, Mwangi J, Liclican A, Niedziela-Majka A, Papalia GA, Wong MH, Leavitt SA, Xu Y, Koditek D, Stepan GJ, Yu H, Pagratis N, Clancy S, Ahmadyar S, Cai TZ, Sellers S, Wolckenhauer SA, Ling J, Callebaut C, Margot N, Ram RR, Liu YP, Hyland R, Sinclair GI, Ruane PJ, Crofoot GE, McDonald CK, Brainard DM, Lad L, Swaminathan S, Sundquist WI, Sakowicz R, Chester AE, Lee WE, Daar ES, Yant SR, Cihlar T. Link JO, et al. Among authors: graupe m. Nature. 2020 Aug;584(7822):614-618. doi: 10.1038/s41586-020-2443-1. Epub 2020 Jul 1. Nature. 2020. PMID: 32612233 Free PMC article. Clinical Trial.
Intensive Care Unit and Acute Care Unit Length of Stay After Congenital Heart Surgery.
Hart SA, Tanel RE, Kipps AK, Hoerst AK, Graupe MA, Cassidy SC, Hlavacek AM, Clabby ML, Bush LB, Zhang W, Banerjee MM, Pasquali SK, Gaies M, Madsen N. Hart SA, et al. Among authors: graupe ma. Ann Thorac Surg. 2020 Oct;110(4):1396-1403. doi: 10.1016/j.athoracsur.2020.01.033. Epub 2020 Feb 28. Ann Thorac Surg. 2020. PMID: 32114048 Free PMC article.
27 results