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Page 1
Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.
Bear AS, Nadler RB, O'Hara MH, Stanton KL, Xu C, Saporito RJ, Rech AJ, Baroja ML, Blanchard T, Elliott MH, Ford MJ, Jones R, Patel S, Brennan A, O'Neil Z, Powell DJ Jr, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. J Clin Invest. 2024 Sep 17;134(21):e175790. doi: 10.1172/JCI175790. J Clin Invest. 2024. PMID: 39287991 Free PMC article. Clinical Trial.
Identification of Core Techniques That Enhance Genome Editing of Human T Cells Expressing Synthetic Antigen Receptors.
Chang JF, Wellhausen N, Engel NW, Landmann JH, Hopkins CR, Salas-McKee J, Bear AS, Selli ME, Agarwal S, Jadlowsky JK, Linette GP, Gill S, June CH, Fraietta JA, Singh N. Chang JF, et al. Among authors: bear as. Cancer Immunol Res. 2024 Sep 3;12(9):1136-1146. doi: 10.1158/2326-6066.CIR-24-0251. Cancer Immunol Res. 2024. PMID: 38869428 Review.
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Smole A, Benton A, Poussin MA, Eiva MA, Mezzanotte C, Camisa B, Greco B, Sharma P, Minutolo NG, Gray F, Bear AS, Baroja ML, Cummins C, Xu C, Sanvito F, Goldgewicht AL, Blanchard T, Rodriguez-Garcia A, Klichinsky M, Bonini C, June CH, Posey AD Jr, Linette GP, Carreno BM, Casucci M, Powell DJ Jr. Smole A, et al. Among authors: bear as. Cancer Cell. 2022 Dec 12;40(12):1470-1487.e7. doi: 10.1016/j.ccell.2022.11.006. Cancer Cell. 2022. PMID: 36513049 Free PMC article.
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Bear AS, Blanchard T, Cesare J, Ford MJ, Richman LP, Xu C, Baroja ML, McCuaig S, Costeas C, Gabunia K, Scholler J, Posey AD Jr, O'Hara MH, Smole A, Powell DJ Jr, Garcia BA, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. Nat Commun. 2021 Jul 16;12(1):4365. doi: 10.1038/s41467-021-24562-2. Nat Commun. 2021. PMID: 34272369 Free PMC article.
Adoptive Cellular Therapy for Solid Tumors.
Bear AS, Fraietta JA, Narayan VK, O'Hara M, Haas NB. Bear AS, et al. Am Soc Clin Oncol Educ Book. 2021 Mar;41:57-65. doi: 10.1200/EDBK_321115. Am Soc Clin Oncol Educ Book. 2021. PMID: 34010040 Free article. Review.
Low rate of infusional toxicity after expanded cord blood transplantation.
Bear AS, Hanley PJ, Bosque DM, Cruz CR, Kaur I, Liu H, Kebriaei P, Hosing C, Rezvani K, Oran B, De Lima MJ, Bollard CM, Shpall EJ. Bear AS, et al. Cytotherapy. 2014 Aug;16(8):1153-7. doi: 10.1016/j.jcyt.2013.12.011. Epub 2014 Feb 28. Cytotherapy. 2014. PMID: 24582458 Free PMC article.
17 results