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Page 1
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader.
Kaneshige A, Yang Y, Bai L, Wang M, Xu R, Mallik L, Chinnaswamy K, Metwally H, Wang Y, McEachern D, Tošović J, Yang CY, Kirchhoff PD, Meagher JL, Stuckey JA, Wang S. Kaneshige A, et al. Among authors: mallik l. J Med Chem. 2024 Sep 23. doi: 10.1021/acs.jmedchem.4c01009. Online ahead of print. J Med Chem. 2024. PMID: 39311434
The Photoactive Excited State of the B12-Based Photoreceptor CarH.
Miller NA, Kaneshiro AK, Konar A, Alonso-Mori R, Britz A, Deb A, Glownia JM, Koralek JD, Mallik L, Meadows JH, Michocki LB, van Driel TB, Koutmos M, Padmanabhan S, Elías-Arnanz M, Kubarych KJ, Marsh ENG, Penner-Hahn JE, Sension RJ. Miller NA, et al. Among authors: mallik l. J Phys Chem B. 2020 Nov 25;124(47):10732-10738. doi: 10.1021/acs.jpcb.0c09428. Epub 2020 Nov 11. J Phys Chem B. 2020. PMID: 33174757
Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures.
Purchal MK, Eyler DE, Tardu M, Franco MK, Korn MM, Khan T, McNassor R, Giles R, Lev K, Sharma H, Monroe J, Mallik L, Koutmos M, Koutmou KS. Purchal MK, et al. Among authors: mallik l. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2109708119. doi: 10.1073/pnas.2109708119. Proc Natl Acad Sci U S A. 2022. PMID: 35058356 Free PMC article.
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sun Y, Florio TJ, Gupta S, Young MC, Marshall QF, Garfinkle SE, Papadaki GF, Truong HV, Mycek E, Li P, Farrel A, Church NL, Jabar S, Beasley MD, Kiefel BR, Yarmarkovich M, Mallik L, Maris JM, Sgourakis NG. Sun Y, et al. Among authors: mallik l. Sci Immunol. 2023 Dec;8(90):eadj5792. doi: 10.1126/sciimmunol.adj5792. Epub 2023 Dec 1. Sci Immunol. 2023. PMID: 38039376 Free PMC article.
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion.
Sun Y, Florio TJ, Gupta S, Young MC, Marshall QF, Garfinkle SE, Papadaki GF, Truong HV, Mycek E, Li P, Farrel A, Church NL, Jabar S, Beasley MD, Kiefel BR, Yarmarkovich M, Mallik L, Maris JM, Sgourakis NG. Sun Y, et al. Among authors: mallik l. bioRxiv [Preprint]. 2023 May 24:2023.05.24.542108. doi: 10.1101/2023.05.24.542108. bioRxiv. 2023. Update in: Sci Immunol. 2023 Dec;8(90):eadj5792. doi: 10.1126/sciimmunol.adj5792 PMID: 37292750 Free PMC article. Updated. Preprint.
15 results