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702 results

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Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors.
Tsimberidou AM, Grothey A, Sigal D, Lenz HJ, Hochster HS, Chao Y, Bai LY, Yen CL, Xu D, Saville MW. Tsimberidou AM, et al. Among authors: lenz hj. Cancer Chemother Pharmacol. 2024 Dec;94(6):787-798. doi: 10.1007/s00280-024-04714-z. Epub 2024 Sep 23. Cancer Chemother Pharmacol. 2024. PMID: 39311947 Free PMC article. Clinical Trial.
Combining antivascular endothelial growth factor and anti-epidermal growth factor receptor antibodies: randomized phase II study of irinotecan and cetuximab with/without ramucirumab in second-line colorectal cancer (ECOG-ACRIN E7208).
Hochster HS, Catalano P, Weitz M, Mitchell EP, Cohen D, O'Dwyer PJ, Faller BA, Kortmansky JS, O'Hara MH, Kricher SM, Lacy J, Lenz HJ, Verma U, Benson AB. Hochster HS, et al. Among authors: lenz hj. J Natl Cancer Inst. 2024 Sep 1;116(9):1487-1494. doi: 10.1093/jnci/djae114. J Natl Cancer Inst. 2024. PMID: 38775718 Clinical Trial.
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial.
Grothey A, Van Cutsem E, Sobrero A, Siena S, Falcone A, Ychou M, Humblet Y, Bouché O, Mineur L, Barone C, Adenis A, Tabernero J, Yoshino T, Lenz HJ, Goldberg RM, Sargent DJ, Cihon F, Cupit L, Wagner A, Laurent D; CORRECT Study Group. Grothey A, et al. Among authors: lenz hj. Lancet. 2013 Jan 26;381(9863):303-12. doi: 10.1016/S0140-6736(12)61900-X. Epub 2012 Nov 22. Lancet. 2013. PMID: 23177514 Clinical Trial.
Integrative multi-omics profiling of colorectal cancer from a Hispanic/Latino cohort of patients.
Waldrup B, Carranza F, Jin Y, Amzaleg Y, Postel M, Craig DW, Carpten JD, Salhia B, Ricker CN, Culver JO, Chavez CE, Stern MC, Baezconde-Garbanati L, Lenz HJ, Velazquez-Villarreal EI. Waldrup B, et al. Among authors: lenz hj. medRxiv [Preprint]. 2024 Nov 15:2024.11.03.24316599. doi: 10.1101/2024.11.03.24316599. medRxiv. 2024. PMID: 39606335 Free PMC article. Preprint.
Nivolumab plus Ipilimumab in Microsatellite-Instability-High Metastatic Colorectal Cancer.
Andre T, Elez E, Van Cutsem E, Jensen LH, Bennouna J, Mendez G, Schenker M, de la Fouchardiere C, Limon ML, Yoshino T, Li J, Lenz HJ, Manzano Mozo JL, Tortora G, Garcia-Carbonero R, Dahan L, Chalabi M, Joshi R, Goekkurt E, Braghiroli MI, Cil T, Cela E, Chen T, Lei M, Dixon M, Abdullaev S, Lonardi S; CheckMate 8HW Investigators. Andre T, et al. Among authors: lenz hj. N Engl J Med. 2024 Nov 28;391(21):2014-2026. doi: 10.1056/NEJMoa2402141. N Engl J Med. 2024. PMID: 39602630 Clinical Trial.
Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling study.
Arai H, Gandhi N, Battaglin F, Wang J, Algaze S, Jayachandran P, Soni S, Zhang W, Yang Y, Millstein J, Lo JH, Sohal D, Goldberg R, Hall MJ, Scott AJ, Hwang JJ, Lou E, Weinberg BA, Marshall J, Goel S, Xiu J, Korn WM, Lenz HJ. Arai H, et al. Among authors: lenz hj. J Immunother Cancer. 2024 Nov 5;12(11):e010326. doi: 10.1136/jitc-2024-010326. J Immunother Cancer. 2024. PMID: 39500526 Free article.
Onvansertib in Combination With Chemotherapy and Bevacizumab in Second-Line Treatment of KRAS-Mutant Metastatic Colorectal Cancer: A Single-Arm, Phase II Trial.
Ahn DH, Ridinger M, Cannon TL, Mendelsohn L, Starr JS, Hubbard JM, Kasi A, Barzi A, Samuëlsz E, Karki A, Subramanian RA, Yemane D, Kim R, Wu CC, Croucher PJP, Smeal T, Kabbinavar FF, Lenz HJ. Ahn DH, et al. Among authors: lenz hj. J Clin Oncol. 2024 Oct 30:JCO2401266. doi: 10.1200/JCO-24-01266. Online ahead of print. J Clin Oncol. 2024. PMID: 39475591
Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer.
McGee HM, Bonner JD, Egelston C, Fu Y, Flores OC, Lindsey S, Shaktah L, Moratalla-Navarro F, Kamal Y, Tsang K, Walker CP, Idos G, McDonnell KJ, Rennert H, Barry EL, Brenner H, Buchanan DD, Campbell PT, Chan AT, Chang-Claude J, Figueiredo JC, Gago-Dominguez M, Hoffmeister M, Hsu L, Huyghe JR, Jenkins MA, Le Marchand L, Lenz HJ, Li L, Lindblom A, Liu Ruby YR, Lynch BM, Newton CC, Offit K, Ogino S, Pamplona RS, Pellatt AJ, Pharoah PDP, Phipps A, Reynaga L, Templeton A, Um CY, Wolk A, Woods MO, Wu AH, Yun Y, Zheng W, Williams TM, Conti DV, Peters U, Lejbkowicz F, Greenson JK, Schmit SL, Gauderman WJ, Hamilton SR, Moreno V, Rennert G, Gruber SB. McGee HM, et al. Among authors: lenz hj. medRxiv [Preprint]. 2024 Sep 26:2024.09.22.24314127. doi: 10.1101/2024.09.22.24314127. medRxiv. 2024. PMID: 39464256 Free PMC article. Preprint.
702 results