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MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors.
Chen S, Hou J, Jaffery R, Guerrero A, Fu R, Shi L, Zheng N, Bohat R, Egan NA, Yu C, Sharif S, Lu Y, He W, Wang S, Gjuka D, Stone EM, Shah PA, Rodon Ahnert J, Chen T, Liu X, Bedford MT, Xu H, Peng W. Chen S, et al. Among authors: lu y. J Immunother Cancer. 2024 Sep 23;12(9):e009600. doi: 10.1136/jitc-2024-009600. J Immunother Cancer. 2024. PMID: 39313308 Free PMC article.
Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice.
Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitán-Peñas H, Guénet JL, Lin K, Lu Y, Chen T, Bedford MT, Dent SY, Richburg JH, Estévez R, Pan HL, Geha RS, Shi Q, Benavides F. Bao J, et al. Among authors: lu y. JCI Insight. 2018 Aug 23;3(16):e99767. doi: 10.1172/jci.insight.99767. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135305 Free PMC article.
CARM1 methylates MED12 to regulate its RNA-binding ability.
Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Treviño LS, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT. Cheng D, et al. Among authors: lu y. Life Sci Alliance. 2018 Sep 19;1(5):e201800117. doi: 10.26508/lsa.201800117. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456381 Free PMC article.
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