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Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing.
Longtin A, Watowich MM, Sadoughi B, Petersen RM, Brosnan SF, Buetow K, Cai Q, Gurven MD, Highland HM, Huang YT, Kaplan H, Kraft TS, Lim YAL, Long J, Melin AD, Roberson J, Ng KS, Stieglitz J, Trumble BC, Venkataraman VV, Wallace IJ, Wu J, Snyder-Mackler N, Jones A, Bick AG, Lea AJ. Longtin A, et al. Among authors: lea aj. bioRxiv [Preprint]. 2024 Sep 9:2024.09.09.612068. doi: 10.1101/2024.09.09.612068. bioRxiv. 2024. PMID: 39314398 Free PMC article. Preprint.
Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations.
Lea AJ, Garcia A, Arevalo J, Ayroles JF, Buetow K, Cole SW, Eid Rodriguez D, Gutierrez M, Highland HM, Hooper PL, Justice A, Kraft T, North KE, Stieglitz J, Kaplan H, Trumble BC, Gurven MD. Lea AJ, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2207544120. doi: 10.1073/pnas.2207544120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574663 Free PMC article.
Evolutionary mismatch and the role of GxE interactions in human disease.
Lea AJ, Clark AG, Dahl AW, Devinsky O, Garcia AR, Golden CD, Kamau J, Kraft TS, Lim YAL, Martins D, Mogoi D, Pajukanta P, Perry G, Pontzer H, Trumble BC, Urlacher SS, Venkataraman VV, Wallace IJ, Gurven M, Lieberman D, Ayroles JF. Lea AJ, et al. ArXiv [Preprint]. 2023 Feb 13:arXiv:2301.05255v2. ArXiv. 2023. PMID: 36713247 Free PMC article. Preprint.
Apolipoprotein-ε4 is associated with higher fecundity in a natural fertility population.
Trumble BC, Charifson M, Kraft T, Garcia AR, Cummings DK, Hooper P, Lea AJ, Eid Rodriguez D, Koebele SV, Buetow K, Beheim B, Minocher R, Gutierrez M, Thomas GS, Gatz M, Stieglitz J, Finch CE, Kaplan H, Gurven M. Trumble BC, et al. Among authors: lea aj. Sci Adv. 2023 Aug 9;9(32):eade9797. doi: 10.1126/sciadv.ade9797. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556539 Free PMC article.
Applying an evolutionary mismatch framework to understand disease susceptibility.
Lea AJ, Clark AG, Dahl AW, Devinsky O, Garcia AR, Golden CD, Kamau J, Kraft TS, Lim YAL, Martins DJ, Mogoi D, Pajukanta P, Perry GH, Pontzer H, Trumble BC, Urlacher SS, Venkataraman VV, Wallace IJ, Gurven M, Lieberman DE, Ayroles JF. Lea AJ, et al. PLoS Biol. 2023 Sep 11;21(9):e3002311. doi: 10.1371/journal.pbio.3002311. eCollection 2023 Sep. PLoS Biol. 2023. PMID: 37695771 Free PMC article.
Immune gene regulation is associated with age and environmental adversity in a nonhuman primate.
Watowich MM, Costa CE, Chiou KL, Goldman EA, Petersen RM, Patterson S; Cayo Biobank Research Unit; Martínez MI, Sterner KN, Horvath JE, Montague MJ, Platt ML, Brent LJN, Higham JP, Lea AJ, Snyder-Mackler N. Watowich MM, et al. Among authors: lea aj. Mol Ecol. 2024 Nov;33(21):e17445. doi: 10.1111/mec.17445. Epub 2024 Jul 20. Mol Ecol. 2024. PMID: 39032090
79 results