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Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients.
Collins CP, Khuat LT, Sckisel GD, Vick LV, Minnar CM, Dunai C, Le CT, Curti BD, Crittenden M, Merleev A, Sheng M, Chao NJ, Maverakis E, Rosario SR, Monjazeb AM, Blazar BR, Longo DL, Canter RJ, Murphy WJ. Collins CP, et al. Among authors: rosario sr. Front Immunol. 2024 Sep 9;15:1429912. doi: 10.3389/fimmu.2024.1429912. eCollection 2024. Front Immunol. 2024. PMID: 39315105 Free PMC article.
Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers.
Rosario SR, Dong B, Zhang Y, Hsiao HH, Isenhart E, Wang J, Siegel EM, Monjazeb AM, Owen DH, Dey P, Tabung FK, Spakowicz DJ, Murphy WJ, Edge S, Yendamuri S, Ibrahimi S, Kolesar JM, McDonald PH, Vadehra D, Churchman M, Liu S, Kalinski P, Mukherjee S. Rosario SR, et al. Int J Mol Sci. 2023 Jun 29;24(13):10847. doi: 10.3390/ijms241310847. Int J Mol Sci. 2023. PMID: 37446025 Free PMC article.
Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer.
Boucher Y, Posada JM, Subudhi S, Kumar AS, Rosario SR, Gu L, Kumra H, Mino-Kenudson M, Talele NP, Duda DG, Fukumura D, Wo JY, Clark JW, Ryan DP, Fernandez-Del Castillo C, Hong TS, Pittet MJ, Jain RK. Boucher Y, et al. Among authors: rosario sr. Clin Cancer Res. 2023 Apr 14;29(8):1605-1619. doi: 10.1158/1078-0432.CCR-22-1630. Clin Cancer Res. 2023. PMID: 36749873 Free PMC article. Clinical Trial.
Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
Odunsi K, Qian F, Lugade AA, Yu H, Geller MA, Fling SP, Kaiser JC, Lacroix AM, D'Amico L, Ramchurren N, Morishima C, Disis ML, Dennis L, Danaher P, Warren S, Nguyen VA, Ravi S, Tsuji T, Rosario S, Zha W, Hutson A, Liu S, Lele S, Zsiros E, McGray AJR, Chiello J, Koya R, Chodon T, Morrison CD, Putluri V, Putluri N, Mager DE, Gunawan R, Cheever MA, Battaglia S, Matsuzaki J. Odunsi K, et al. Sci Transl Med. 2022 Mar 16;14(636):eabg8402. doi: 10.1126/scitranslmed.abg8402. Epub 2022 Mar 16. Sci Transl Med. 2022. PMID: 35294258 Free PMC article.
Combined BRCA2 and MAGEC3 Expression Predict Outcome in Advanced Ovarian Cancers.
Omole EB, Aijaz I, Ellegate J Jr, Isenhart E, Desouki MM, Mastri M, Humphrey K, Dougherty EM, Rosario SR, Nastiuk KL, Ohm JE, Eng KH. Omole EB, et al. Among authors: rosario sr. Cancers (Basel). 2022 Sep 28;14(19):4724. doi: 10.3390/cancers14194724. Cancers (Basel). 2022. PMID: 36230652 Free PMC article.
Age-related increase of CD38 directs osteoclastogenic potential of monocytic myeloid-derived suppressor cells through mitochondrial dysfunction in male mice.
Thiyagarajan R, Zhang L, Glover OD, Kwack KH, Ahmed S, Murray E, Yellapu NK, Bard J, Seldeen KL, Rosario SR, Troen BR, Kirkwood KL. Thiyagarajan R, et al. Among authors: rosario sr. Aging Cell. 2024 Nov;23(11):e14298. doi: 10.1111/acel.14298. Epub 2024 Aug 23. Aging Cell. 2024. PMID: 39180173 Free PMC article.
41 results