Jackson CJ - Search Results

1

1.3 Å Crystal Structure of E. coli Peptidyl-Prolyl Isomerase B with Uniform Substitution of Valine by (2S,3S)-4-Fluorovaline Reveals Structure Conservation and Multiple Staggered Rotamers of CH₂F Groups.

Frkic RL, Tan YJ, Maleckis A, Chilton NF, Otting G, Jackson CJ. Frkic RL, et al. Among authors: jackson cj. Biochemistry. 2024 Oct 15;63(20):2602-2608. doi: 10.1021/acs.biochem.4c00345. Epub 2024 Sep 24. Biochemistry. 2024. PMID: 39316701

2

Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides.

Smith OB, Frkic RL, Rahman MG, Jackson CJ, Kaczmarski JA. Smith OB, et al. Among authors: jackson cj. Biochemistry. 2024 May 21;63(10):1322-1334. doi: 10.1021/acs.biochem.4c00096. Epub 2024 May 2. Biochemistry. 2024. PMID: 38696389

3

Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.

Frkic RL, Tan YJ, Abdelkader EH, Maleckis A, Tarcoveanu E, Nitsche C, Otting G, Jackson CJ. Frkic RL, et al. Among authors: jackson cj. Biochemistry. 2024 Jun 4;63(11):1388-1394. doi: 10.1021/acs.biochem.4c00081. Epub 2024 May 14. Biochemistry. 2024. PMID: 38742763

4

Through-Space Scalar ¹⁹F-¹⁹F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.

Orton HW, Qianzhu H, Abdelkader EH, Habel EI, Tan YJ, Frkic RL, Jackson CJ, Huber T, Otting G. Orton HW, et al. Among authors: jackson cj. J Am Chem Soc. 2021 Nov 24;143(46):19587-19598. doi: 10.1021/jacs.1c10104. Epub 2021 Nov 15. J Am Chem Soc. 2021. PMID: 34780162

5

Asymmetric Ene-Reduction of α,β-Unsaturated Compounds by F₄₂₀-Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis.

Kang SW, Antoney J, Frkic RL, Lupton DW, Speight R, Scott C, Jackson CJ. Kang SW, et al. Among authors: jackson cj. Biochemistry. 2023 Feb 7;62(3):873-891. doi: 10.1021/acs.biochem.2c00557. Epub 2022 Dec 5. Biochemistry. 2023. PMID: 36637210

6

Increasing the Soluble Expression and Whole-Cell Activity of the Plastic-Degrading Enzyme MHETase through Consensus Design.

Saunders JW, Damry AM, Vongsouthi V, Spence MA, Frkic RL, Gomez C, Yates PA, Matthews DS, Tokuriki N, McLeod MD, Jackson CJ. Saunders JW, et al. Among authors: jackson cj. Biochemistry. 2024 Jul 2;63(13):1663-1673. doi: 10.1021/acs.biochem.4c00165. Epub 2024 Jun 17. Biochemistry. 2024. PMID: 38885634

7

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction.

Abdelkader EH, Qianzhu H, George J, Frkic RL, Jackson CJ, Nitsche C, Otting G, Huber T. Abdelkader EH, et al. Among authors: jackson cj. Angew Chem Int Ed Engl. 2022 Mar 21;61(13):e202114154. doi: 10.1002/anie.202114154. Epub 2022 Feb 11. Angew Chem Int Ed Engl. 2022. PMID: 35102680 Free PMC article.

8

Protein engineering with unnatural amino acids.

Zhang WH, Otting G, Jackson CJ. Zhang WH, et al. Among authors: jackson cj. Curr Opin Struct Biol. 2013 Aug;23(4):581-7. doi: 10.1016/j.sbi.2013.06.009. Epub 2013 Jul 5. Curr Opin Struct Biol. 2013. PMID: 23835227 Review.

9

Iron(III) located in the dinuclear metallo-β-lactamase IMP-1 by pseudocontact shifts.

Carruthers TJ, Carr PD, Loh CT, Jackson CJ, Otting G. Carruthers TJ, et al. Among authors: jackson cj. Angew Chem Int Ed Engl. 2014 Dec 15;53(51):14269-72. doi: 10.1002/anie.201408693. Epub 2014 Oct 15. Angew Chem Int Ed Engl. 2014. PMID: 25320022

10

Antiviral cyclic peptides targeting the main protease of SARS-CoV-2.

Johansen-Leete J, Ullrich S, Fry SE, Frkic R, Bedding MJ, Aggarwal A, Ashhurst AS, Ekanayake KB, Mahawaththa MC, Sasi VM, Luedtke S, Ford DJ, O'Donoghue AJ, Passioura T, Larance M, Otting G, Turville S, Jackson CJ, Nitsche C, Payne RJ. Johansen-Leete J, et al. Among authors: jackson cj. Chem Sci. 2022 Feb 28;13(13):3826-3836. doi: 10.1039/d1sc06750h. eCollection 2022 Mar 30. Chem Sci. 2022. PMID: 35432913 Free PMC article.

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