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Page 1
IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis.
Zhang P, Liu J, Lee A, Tsaur I, Ohira M, Duong V, Vo N, Watari K, Su H, Kim JY, Gu L, Zhu M, Shalapour S, Hosseini M, Bandyopadhyay G, Zeng S, Llorente C, Zhao HN, Lamichhane S, Mohan S, Dorrestein PC, Olefsky JM, Schnabl B, Soroosh P, Karin M. Zhang P, et al. Among authors: soroosh p. Cell Metab. 2024 Oct 1;36(10):2341-2354.e6. doi: 10.1016/j.cmet.2024.08.012. Epub 2024 Sep 23. Cell Metab. 2024. PMID: 39317186 Free article.
Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2.
Ganguly S, Rosenthal SB, Ishizuka K, Troutman TD, Rohm TV, Khader N, Aleman-Muench G, Sano Y, Archilei S, Soroosh P, Olefsky JM, Feldstein AE, Kisseleva T, Loomba R, Glass CK, Brenner DA, Dhar D. Ganguly S, et al. Among authors: soroosh p. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2405746121. doi: 10.1073/pnas.2405746121. Epub 2024 Aug 22. Proc Natl Acad Sci U S A. 2024. PMID: 39172787 Free PMC article.
Proinflammatory polarization of monocytes by particulate air pollutants is mediated by induction of trained immunity in pediatric asthma.
Movassagh H, Prunicki M, Kaushik A, Zhou X, Dunham D, Smith EM, He Z, Aleman Muench GR, Shi M, Weimer AK, Cao S, Andorf S, Feizi A, Snyder MP, Soroosh P, Mellins ED, Nadeau KC. Movassagh H, et al. Among authors: soroosh p. Allergy. 2023 Jul;78(7):1922-1933. doi: 10.1111/all.15692. Epub 2023 Mar 16. Allergy. 2023. PMID: 36929161
Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells.
Helou DG, Quach C, Fung M, Painter JD, Hurrell BP, Eddie Loh YH, Howard E, Shafiei-Jahani P, Soroosh P, Sharpe AH, Akbari O. Helou DG, et al. Among authors: soroosh p. J Allergy Clin Immunol. 2023 Feb;151(2):526-538.e8. doi: 10.1016/j.jaci.2022.07.022. Epub 2022 Aug 11. J Allergy Clin Immunol. 2023. PMID: 35963455 Free PMC article.
Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23.
Galle-Treger L, Helou DG, Quach C, Howard E, Hurrell BP, Muench GRA, Shafiei-Jahani P, Painter JD, Iorga A, Dara L, Emamaullee J, Golden-Mason L, Rosen HR, Soroosh P, Akbari O. Galle-Treger L, et al. Among authors: soroosh p. Nat Commun. 2022 Mar 17;13(1):1440. doi: 10.1038/s41467-022-29174-y. Nat Commun. 2022. PMID: 35301333 Free PMC article.
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother TR, Tourtellotte WG, Zhang Y, Aleman-Muench GR, Lewis G, Chen W, Kang S, Luevanos M, Trudler D, Lipton SA, Soroosh P, Teijaro J, de la Torre JC, Arditi M, Karin M, Sanchez-Lopez E. Xian H, et al. Among authors: soroosh p. Immunity. 2021 Jul 13;54(7):1463-1477.e11. doi: 10.1016/j.immuni.2021.05.004. Epub 2021 Jun 10. Immunity. 2021. PMID: 34115964 Free PMC article.
47 results