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Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.
Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Among authors: metwaly am. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
Eissa IH, Metwaly AM, Belal A, Mehany ABM, Ayyad RR, El-Adl K, Mahdy HA, Taghour MS, El-Gamal KMA, El-Sawah ME, Elmetwally SA, Elhendawy MA, Radwan MM, ElSohly MA. Eissa IH, et al. Among authors: metwaly am. Arch Pharm (Weinheim). 2019 Nov;352(11):e1900123. doi: 10.1002/ardp.201900123. Epub 2019 Aug 29. Arch Pharm (Weinheim). 2019. PMID: 31463953
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.
Mahdy HA, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, El-Gamal KMA, El-Sharkawy A, Elhendawy MA, Radwan MM, Elsohly MA, Eissa IH. Mahdy HA, et al. Among authors: metwaly am. Bioorg Chem. 2020 Jan;94:103422. doi: 10.1016/j.bioorg.2019.103422. Epub 2019 Nov 12. Bioorg Chem. 2020. PMID: 31812261
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.
El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Khalifa MM, Belal A, Rashed M, El-Sharkawy A, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH. El-Helby AA, et al. Among authors: metwaly am. Bioorg Chem. 2020 Oct;103:104233. doi: 10.1016/j.bioorg.2020.104233. Epub 2020 Aug 26. Bioorg Chem. 2020. PMID: 32882440
96 results