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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.
Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas AS, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M. Wani AH, et al. Among authors: milberg w. BMC Med Genomics. 2024 Sep 27;17(1):235. doi: 10.1186/s12920-024-02002-6. BMC Med Genomics. 2024. PMID: 39334086 Free PMC article.
An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.
Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, Garrett ME, Boks MP, Geuze E, Grant GA, Hauser MA, Kessler RC, Kimbrel NA, Maihofer AX, Marx CE, Qin XJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Hayes JP, Verfaellie M; Traumatic Stress Brain Study Group. Logue MW, et al. Among authors: milberg wp. Clin Epigenetics. 2020 Mar 14;12(1):46. doi: 10.1186/s13148-020-0820-0. Clin Epigenetics. 2020. PMID: 32171335 Free PMC article.
PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L.
Katrinli S, Zheng Y, Gautam A, Hammamieh R, Yang R, Venkateswaran S, Kilaru V, Lori A, Hinrichs R, Powers A, Gillespie CF, Wingo AP, Michopoulos V, Jovanovic T, Wolf EJ, McGlinchey RE, Milberg WP, Miller MW, Kugathasan S, Jett M, Logue MW, Ressler KJ, Smith AK. Katrinli S, et al. Among authors: milberg wp. Brain Behav Immun. 2021 Jan;91:429-436. doi: 10.1016/j.bbi.2020.10.023. Epub 2020 Nov 3. Brain Behav Immun. 2021. PMID: 33152445 Free PMC article.
SKA2 methylation is associated with decreased prefrontal cortical thickness and greater PTSD severity among trauma-exposed veterans.
Sadeh N, Spielberg JM, Logue MW, Wolf EJ, Smith AK, Lusk J, Hayes JP, Sperbeck E, Milberg WP, McGlinchey RE, Salat DH, Carter WC, Stone A, Schichman SA, Humphries DE, Miller MW. Sadeh N, et al. Among authors: milberg wp. Mol Psychiatry. 2016 Mar;21(3):357-63. doi: 10.1038/mp.2015.134. Epub 2015 Sep 1. Mol Psychiatry. 2016. PMID: 26324104 Free PMC article.
Accelerated DNA methylation age: Associations with PTSD and neural integrity.
Wolf EJ, Logue MW, Hayes JP, Sadeh N, Schichman SA, Stone A, Salat DH, Milberg W, McGlinchey R, Miller MW. Wolf EJ, et al. Among authors: milberg w. Psychoneuroendocrinology. 2016 Jan;63:155-62. doi: 10.1016/j.psyneuen.2015.09.020. Epub 2015 Sep 30. Psychoneuroendocrinology. 2016. PMID: 26447678 Free PMC article.
Posttraumatic stress disorder symptom severity is associated with reduced default mode network connectivity in individuals with elevated genetic risk for psychopathology.
Miller DR, Logue MW, Wolf EJ, Maniates H, Robinson ME, Hayes JP, Stone A, Schichman S, McGlinchey RE, Milberg WP, Miller MW. Miller DR, et al. Among authors: milberg wp. Depress Anxiety. 2017 Jul;34(7):632-640. doi: 10.1002/da.22633. Epub 2017 May 11. Depress Anxiety. 2017. PMID: 28494120 Free PMC article.
246 results