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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.
Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas AS, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M. Wani AH, et al. Among authors: nugent nr. BMC Med Genomics. 2024 Sep 27;17(1):235. doi: 10.1186/s12920-024-02002-6. BMC Med Genomics. 2024. PMID: 39334086 Free PMC article.
Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
Duncan LE, Ratanatharathorn A, Aiello AE, Almli LM, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bierut LJ, Bisson J, Bradley B, Chen CY, Dalvie S, Farrer LA, Galea S, Garrett ME, Gelernter JE, Guffanti G, Hauser MA, Johnson EO, Kessler RC, Kimbrel NA, King A, Koen N, Kranzler HR, Logue MW, Maihofer AX, Martin AR, Miller MW, Morey RA, Nugent NR, Rice JP, Ripke S, Roberts AL, Saccone NL, Smoller JW, Stein DJ, Stein MB, Sumner JA, Uddin M, Ursano RJ, Wildman DE, Yehuda R, Zhao H, Daly MJ, Liberzon I, Ressler KJ, Nievergelt CM, Koenen KC. Duncan LE, et al. Among authors: nugent nr. Mol Psychiatry. 2018 Mar;23(3):666-673. doi: 10.1038/mp.2017.77. Epub 2017 Apr 25. Mol Psychiatry. 2018. PMID: 28439101 Free PMC article.
Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.
Ratanatharathorn A, Boks MP, Maihofer AX, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bromet E, Dennis M, Garrett ME, Geuze E, Guffanti G, Hauser MA, Kilaru V, Kimbrel NA, Koenen KC, Kuan PF, Logue MW, Luft BJ, Miller MW, Mitchell C, Nugent NR, Ressler KJ, Rutten BPF, Stein MB, Vermetten E, Vinkers CH, Youssef NA; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup; Uddin M, Nievergelt CM, Smith AK. Ratanatharathorn A, et al. Among authors: nugent nr. Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):619-630. doi: 10.1002/ajmg.b.32568. Epub 2017 Jul 10. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28691784 Free PMC article.
The Role of the Hippocampus in Predicting Future Posttraumatic Stress Disorder Symptoms in Recently Traumatized Civilians.
van Rooij SJH, Stevens JS, Ely TD, Hinrichs R, Michopoulos V, Winters SJ, Ogbonmwan YE, Shin J, Nugent NR, Hudak LA, Rothbaum BO, Ressler KJ, Jovanovic T. van Rooij SJH, et al. Among authors: nugent nr. Biol Psychiatry. 2018 Jul 15;84(2):106-115. doi: 10.1016/j.biopsych.2017.09.005. Epub 2017 Sep 20. Biol Psychiatry. 2018. PMID: 29110899 Free PMC article.
Traumatic stress and accelerated DNA methylation age: A meta-analysis.
Wolf EJ, Maniates H, Nugent N, Maihofer AX, Armstrong D, Ratanatharathorn A, Ashley-Koch AE, Garrett M, Kimbrel NA, Lori A, Va Mid-Atlantic Mirecc Workgroup, Aiello AE, Baker DG, Beckham JC, Boks MP, Galea S, Geuze E, Hauser MA, Kessler RC, Koenen KC, Miller MW, Ressler KJ, Risbrough V, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Uddin M, Smith AK, Nievergelt CM, Logue MW. Wolf EJ, et al. Psychoneuroendocrinology. 2018 Jun;92:123-134. doi: 10.1016/j.psyneuen.2017.12.007. Epub 2017 Dec 27. Psychoneuroendocrinology. 2018. PMID: 29452766 Free PMC article.
102 results