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Page 1
Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.
Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas AS, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M. Wani AH, et al. Among authors: smith ak. BMC Med Genomics. 2024 Sep 27;17(1):235. doi: 10.1186/s12920-024-02002-6. BMC Med Genomics. 2024. PMID: 39334086 Free PMC article.
Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.
Ratanatharathorn A, Boks MP, Maihofer AX, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bromet E, Dennis M, Garrett ME, Geuze E, Guffanti G, Hauser MA, Kilaru V, Kimbrel NA, Koenen KC, Kuan PF, Logue MW, Luft BJ, Miller MW, Mitchell C, Nugent NR, Ressler KJ, Rutten BPF, Stein MB, Vermetten E, Vinkers CH, Youssef NA; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup; Uddin M, Nievergelt CM, Smith AK. Ratanatharathorn A, et al. Among authors: smith ak. Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):619-630. doi: 10.1002/ajmg.b.32568. Epub 2017 Jul 10. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28691784 Free PMC article.
Traumatic stress and accelerated DNA methylation age: A meta-analysis.
Wolf EJ, Maniates H, Nugent N, Maihofer AX, Armstrong D, Ratanatharathorn A, Ashley-Koch AE, Garrett M, Kimbrel NA, Lori A, Va Mid-Atlantic Mirecc Workgroup, Aiello AE, Baker DG, Beckham JC, Boks MP, Galea S, Geuze E, Hauser MA, Kessler RC, Koenen KC, Miller MW, Ressler KJ, Risbrough V, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Uddin M, Smith AK, Nievergelt CM, Logue MW. Wolf EJ, et al. Among authors: smith ak. Psychoneuroendocrinology. 2018 Jun;92:123-134. doi: 10.1016/j.psyneuen.2017.12.007. Epub 2017 Dec 27. Psychoneuroendocrinology. 2018. PMID: 29452766 Free PMC article.
Successful treatment of post-traumatic stress disorder reverses DNA methylation marks.
Vinkers CH, Geuze E, van Rooij SJH, Kennis M, Schür RR, Nispeling DM, Smith AK, Nievergelt CM, Uddin M, Rutten BPF, Vermetten E, Boks MP. Vinkers CH, et al. Among authors: smith ak. Mol Psychiatry. 2021 Apr;26(4):1264-1271. doi: 10.1038/s41380-019-0549-3. Epub 2019 Oct 23. Mol Psychiatry. 2021. PMID: 31645664
Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder.
Snijders C, Maihofer AX, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Jain S, Kessler RC, Pishva E, Risbrough VB, Stein MB, Ursano RJ, Vermetten E, Vinkers CH; PGC PTSD EWAS Consortium; Smith AK, Uddin M, Rutten BPF, Nievergelt CM. Snijders C, et al. Among authors: smith ak. Clin Epigenetics. 2020 Jan 13;12(1):11. doi: 10.1186/s13148-019-0798-7. Clin Epigenetics. 2020. PMID: 31931860 Free PMC article.
An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.
Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, Garrett ME, Boks MP, Geuze E, Grant GA, Hauser MA, Kessler RC, Kimbrel NA, Maihofer AX, Marx CE, Qin XJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Hayes JP, Verfaellie M; Traumatic Stress Brain Study Group. Logue MW, et al. Among authors: smith ak. Clin Epigenetics. 2020 Mar 14;12(1):46. doi: 10.1186/s13148-020-0820-0. Clin Epigenetics. 2020. PMID: 32171335 Free PMC article.
PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L.
Katrinli S, Zheng Y, Gautam A, Hammamieh R, Yang R, Venkateswaran S, Kilaru V, Lori A, Hinrichs R, Powers A, Gillespie CF, Wingo AP, Michopoulos V, Jovanovic T, Wolf EJ, McGlinchey RE, Milberg WP, Miller MW, Kugathasan S, Jett M, Logue MW, Ressler KJ, Smith AK. Katrinli S, et al. Among authors: smith ak. Brain Behav Immun. 2021 Jan;91:429-436. doi: 10.1016/j.bbi.2020.10.023. Epub 2020 Nov 3. Brain Behav Immun. 2021. PMID: 33152445 Free PMC article.
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.
Smith AK, Ratanatharathorn A, Maihofer AX, Naviaux RK, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Boks MP, Bromet E, Dennis M, Galea S, Garrett ME, Geuze E, Guffanti G, Hauser MA, Katrinli S, Kilaru V, Kessler RC, Kimbrel NA, Koenen KC, Kuan PF, Li K, Logue MW, Lori A, Luft BJ, Miller MW, Naviaux JC, Nugent NR, Qin X, Ressler KJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Wang L, Youssef NA; INTRuST Clinical Consortium; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup; Uddin M, Nievergelt CM. Smith AK, et al. Nat Commun. 2020 Nov 24;11(1):5965. doi: 10.1038/s41467-020-19615-x. Nat Commun. 2020. PMID: 33235198 Free PMC article.
Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress.
Katrinli S, Maihofer AX, Wani AH, Pfeiffer JR, Ketema E, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Kessler RC, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Logue MW, Nievergelt CM, Smith AK, Uddin M. Katrinli S, et al. Among authors: smith ak. Mol Psychiatry. 2022 Mar;27(3):1720-1728. doi: 10.1038/s41380-021-01398-2. Epub 2022 Jan 7. Mol Psychiatry. 2022. PMID: 34992238 Free PMC article.
674 results