Al Adem K - Search Results

1

Identification of novel allosteric sites of SARS-CoV-2 papain-like protease (PLpro) for the development of COVID-19 antivirals.

Ferreira JC, Villanueva AJ, Al Adem K, Fadl S, Alzyoud L, Ghattas MA, Rabeh WM. Ferreira JC, et al. Among authors: al adem k. J Biol Chem. 2024 Sep 27;300(11):107821. doi: 10.1016/j.jbc.2024.107821. Online ahead of print. J Biol Chem. 2024. PMID: 39342997 Free PMC article.

2

3-chymotrypsin-like protease in SARS-CoV-2.

Al Adem K, Ferreira JC, Villanueva AJ, Fadl S, El-Sadaany F, Masmoudi I, Gidiya Y, Gurudza T, Cardoso THS, Saksena NK, Rabeh WM. Al Adem K, et al. Biosci Rep. 2024 Aug 28;44(8):BSR20231395. doi: 10.1042/BSR20231395. Biosci Rep. 2024. PMID: 39036877 Free PMC article. Review.

3

Inhibition of the Early-Stage Cross-Amyloid Aggregation of Amyloid-β and IAPP via EGCG: Insights from Molecular Dynamics Simulations.

Srivastava A, Al Adem K, Shanti A, Lee S, Abedrabbo S, Homouz D. Srivastava A, et al. Among authors: al adem k. ACS Omega. 2024 Jul 3;9(28):30256-30269. doi: 10.1021/acsomega.4c00500. eCollection 2024 Jul 16. ACS Omega. 2024. PMID: 39035938 Free PMC article.

4

Residues in the fructose-binding pocket are required for ketohexokinase-A activity.

Ferreira JC, Villanueva AJ, Fadl S, Al Adem K, Cinviz ZN, Nedyalkova L, Cardoso THS, Andrade ME, Saksena NK, Sensoy O, Rabeh WM. Ferreira JC, et al. Among authors: al adem k. J Biol Chem. 2024 Aug;300(8):107538. doi: 10.1016/j.jbc.2024.107538. Epub 2024 Jul 4. J Biol Chem. 2024. PMID: 38971308 Free PMC article.

5

Optoacoustic biomarkers of lipids, hemorrhage and inflammation in carotid atherosclerosis.

Karlas A, Fasoula NA, Kallmayer M, Schäffer C, Angelis G, Katsouli N, Reidl M, Duelmer F, Al Adem K, Hadjileontiadis L, Eckstein HH, Ntziachristos V. Karlas A, et al. Among authors: al adem k. Front Cardiovasc Med. 2023 Nov 9;10:1210032. doi: 10.3389/fcvm.2023.1210032. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 38028502 Free PMC article. Review.

6

Key Allosteric and Active Site Residues of SARS-CoV-2 3CLpro Are Promising Drug Targets.

Al Adem K, Ferreira JC, Fadl S, Mustafa M, Rabeh WM. Al Adem K, et al. Biochem J. 2023 May 31:BCJ20230027. doi: 10.1042/BCJ20230027. Online ahead of print. Biochem J. 2023. PMID: 37254750

7

Structural polymorphism and cytotoxicity of brain-derived β-amyloid extracts.

Al Adem K, Lee S. Al Adem K, et al. Protein Sci. 2023 May;32(5):e4639. doi: 10.1002/pro.4639. Protein Sci. 2023. PMID: 37051675 Free PMC article. Review.

8

pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity.

Al Adem K, Ferreira JC, Fadl S, Rabeh WM. Al Adem K, et al. J Biol Chem. 2023 Feb;299(2):102790. doi: 10.1016/j.jbc.2022.102790. Epub 2022 Dec 9. J Biol Chem. 2023. PMID: 36509143 Free PMC article.

9

2D MXenes for controlled releases of therapeutic proteins.

Seitak A, Shanti A, Al Adem K, Farid N, Luo S, Iskandarov J, Karanikolos GN, Liao K, Chan V, Lee S. Seitak A, et al. Among authors: al adem k. J Biomed Mater Res A. 2023 Apr;111(4):514-526. doi: 10.1002/jbm.a.37469. Epub 2022 Nov 13. J Biomed Mater Res A. 2023. PMID: 36371793

10

Linking Alzheimer's Disease and Type 2 Diabetes: Characterization and Inhibition of Cytotoxic Aβ and IAPP Hetero-Aggregates.

Al Adem K, Shanti A, Srivastava A, Homouz D, Thomas SA, Khair M, Stefanini C, Chan V, Kim TY, Lee S. Al Adem K, et al. Front Mol Biosci. 2022 Mar 17;9:842582. doi: 10.3389/fmolb.2022.842582. eCollection 2022. Front Mol Biosci. 2022. PMID: 35372522 Free PMC article.

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