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Validation of surrogate markers in multiple randomized clinical trials with repeated measurements: canonical correlation approach.
Alonso A, Geys H, Molenberghs G, Kenward MG, Vangeneugden T. Alonso A, et al. Biometrics. 2004 Dec;60(4):845-53. doi: 10.1111/j.0006-341X.2004.00239.x. Biometrics. 2004. PMID: 15606404
Part of the recent literature on the evaluation of biomarkers as surrogate endpoints starts from a multitrial context, which leads to a definition of validity in terms of the quality of both trial-level and individual-level association between the surrogate and true …
Part of the recent literature on the evaluation of biomarkers as surrogate endpoints starts from a multitrial context, which leads to …
A unifying approach for surrogate marker validation based on Prentice's criteria.
Alonso A, Molenberghs G, Geys H, Buyse M, Vangeneugden T. Alonso A, et al. Stat Med. 2006 Jan 30;25(2):205-21. doi: 10.1002/sim.2315. Stat Med. 2006. PMID: 16220497
Part of the recent literature on the evaluation of surrogate endpoints starts from a multi-trial approach which leads to a definition of validity in terms of the quality of both trial-level and individual-level association between a potential surrogate and …
Part of the recent literature on the evaluation of surrogate endpoints starts from a multi-trial approach which leads to a def …
Information-theory based surrogate marker evaluation from several randomized clinical trials with continuous true and binary surrogate endpoints.
Pryseley A, Tilahun A, Alonso A, Molenberghs G. Pryseley A, et al. Among authors: alonso a. Clin Trials. 2007;4(6):587-97. doi: 10.1177/1740774507084979. Clin Trials. 2007. PMID: 18042568 Review.
BACKGROUND: Surrogate endpoints potentially reduce the duration and/or increase the amount of information available in a study, thereby diminishing patient burden and cost. They may also increase the effectiveness and reliability of research, through beneficial impact on n …
BACKGROUND: Surrogate endpoints potentially reduce the duration and/or increase the amount of information available in a study, there …
3,419 results