Roberson ED - Search Results

1

Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia.

Kashyap SN, Fox SN, Wilson KI, Murchison CF, Ambaw YA, Walther TC, Farese RV, Arrant AE, Roberson ED. Kashyap SN, et al. Among authors: roberson ed. bioRxiv [Preprint]. 2024 Sep 16:2024.09.15.613118. doi: 10.1101/2024.09.15.613118. bioRxiv. 2024. PMID: 39345608 Free PMC article. Preprint.

2

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations.

Arrant AE, Roth JR, Boyle NR, Kashyap SN, Hoffmann MQ, Murchison CF, Ramos EM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Roberson ED. Arrant AE, et al. Among authors: roberson ed. Acta Neuropathol Commun. 2019 Dec 23;7(1):218. doi: 10.1186/s40478-019-0872-6. Acta Neuropathol Commun. 2019. PMID: 31870439 Free PMC article.

3

Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations.

Kashyap SN, Boyle NR, Roberson ED. Kashyap SN, et al. Among authors: roberson ed. Neurotherapeutics. 2023 Jan;20(1):140-153. doi: 10.1007/s13311-023-01348-6. Epub 2023 Feb 13. Neurotherapeutics. 2023. PMID: 36781744 Free PMC article. Review.

4

MicroRNA-124 modulates social behavior in frontotemporal dementia.

Arrant AE, Roberson ED. Arrant AE, et al. Among authors: roberson ed. Nat Med. 2014 Dec;20(12):1381-3. doi: 10.1038/nm.3768. Nat Med. 2014. PMID: 25473917

5

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.

Arrant AE, Onyilo VC, Unger DE, Roberson ED. Arrant AE, et al. Among authors: roberson ed. J Neurosci. 2018 Feb 28;38(9):2341-2358. doi: 10.1523/JNEUROSCI.3081-17.2018. Epub 2018 Jan 29. J Neurosci. 2018. PMID: 29378861 Free PMC article.

6

Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice.

Arrant AE, Patel AR, Roberson ED. Arrant AE, et al. Among authors: roberson ed. eNeuro. 2015 May-Jun;2(3):ENEURO.0061-14.2015. doi: 10.1523/ENEURO.0061-14.2015. eNeuro. 2015. PMID: 26361634 Free PMC article.

7

Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia.

Arrant AE, Filiano AJ, Unger DE, Young AH, Roberson ED. Arrant AE, et al. Among authors: roberson ed. Brain. 2017 May 1;140(5):1447-1465. doi: 10.1093/brain/awx060. Brain. 2017. PMID: 28379303 Free PMC article.

8

Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice.

Arrant AE, Filiano AJ, Patel AR, Hoffmann MQ, Boyle NR, Kashyap SN, Onyilo VC, Young AH, Roberson ED. Arrant AE, et al. Among authors: roberson ed. Neurobiol Dis. 2019 Apr;124:152-162. doi: 10.1016/j.nbd.2018.11.011. Epub 2018 Nov 15. Neurobiol Dis. 2019. PMID: 30448285 Free PMC article.

9

Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia.

Kurnellas M, Mitra A, Schwabe T, Paul R, Arrant AE, Roberson ED, Ward M, Yeh F, Long H, Rosenthal A. Kurnellas M, et al. Among authors: roberson ed. J Transl Med. 2023 Jun 15;21(1):387. doi: 10.1186/s12967-023-04251-y. J Transl Med. 2023. PMID: 37322482 Free PMC article.

10

Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients.

Arrant AE, Davis SE, Vollmer RM, Murchison CF, Mobley JA, Nana AL, Spina S, Grinberg LT, Karydas AM, Miller BL, Seeley WW, Roberson ED. Arrant AE, et al. Among authors: roberson ed. Ann Clin Transl Neurol. 2020 Dec;7(12):2433-2449. doi: 10.1002/acn3.51242. Epub 2020 Nov 16. Ann Clin Transl Neurol. 2020. PMID: 33197149 Free PMC article.

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