Yu HY - Search Results

1

Exploring Structure-Activity Relationships and Modes of Action of Laterocidine.

Thombare VJ, Swarbrick JD, Azad MAK, Zhu Y, Lu J, Yu HY, Wickremasinghe H, He X, Bandiatmakur M, Li R, Bergen PJ, Velkov T, Wang J, Roberts KD, Li J, Patil NA. Thombare VJ, et al. Among authors: yu hy. ACS Cent Sci. 2024 Aug 6;10(9):1703-1717. doi: 10.1021/acscentsci.4c00776. eCollection 2024 Sep 25. ACS Cent Sci. 2024. PMID: 39345814 Free PMC article.

2

A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii.

Jiang X, Patil NA, Azad MAK, Wickremasinghe H, Yu H, Zhao J, Zhang X, Li M, Gong B, Wan L, Ma W, Thompson PE, Yang K, Yuan B, Schreiber F, Wang L, Velkov T, Roberts KD, Li J. Jiang X, et al. Chem Sci. 2021 Aug 19;12(36):12211-12220. doi: 10.1039/d1sc03460j. eCollection 2021 Sep 22. Chem Sci. 2021. PMID: 34667587 Free PMC article.

3

Polymyxin Triple Combinations against Polymyxin-Resistant, Multidrug-Resistant, KPC-Producing Klebsiella pneumoniae.

Aye SM, Galani I, Yu H, Wang J, Chen K, Wickremasinghe H, Karaiskos I, Bergen PJ, Zhao J, Velkov T, Giamarellou H, Lin YW, Tsuji BT, Li J. Aye SM, et al. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e00246-20. doi: 10.1128/AAC.00246-20. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32393492 Free PMC article.

4

Polymyxin dose tunes the evolutionary dynamics of resistance in multidrug-resistant Acinetobacter baumannii.

Zhao J, Zhu Y, Lin YW, Yu H, Wickremasinghe H, Han J, Velkov T, McDonald MJ, Li J. Zhao J, et al. Clin Microbiol Infect. 2022 Jul;28(7):1026.e1-1026.e5. doi: 10.1016/j.cmi.2022.02.043. Epub 2022 Mar 10. Clin Microbiol Infect. 2022. PMID: 35283314 Free article.

5

Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol.

Abdul Rahim N, Cheah SE, Johnson MD, Yu H, Sidjabat HE, Boyce J, Butler MS, Cooper MA, Fu J, Paterson DL, Nation RL, Bergen PJ, Velkov T, Li J. Abdul Rahim N, et al. J Antimicrob Chemother. 2015 Sep;70(9):2589-97. doi: 10.1093/jac/dkv135. Epub 2015 May 28. J Antimicrob Chemother. 2015. PMID: 26023209 Free PMC article.

6

Activity of colistin combined with doripenem at clinically relevant concentrations against multidrug-resistant Pseudomonas aeruginosa in an in vitro dynamic biofilm model.

Lora-Tamayo J, Murillo O, Bergen PJ, Nation RL, Poudyal A, Luo X, Yu HY, Ariza J, Li J. Lora-Tamayo J, et al. Among authors: yu hy. J Antimicrob Chemother. 2014 Sep;69(9):2434-42. doi: 10.1093/jac/dku151. Epub 2014 May 15. J Antimicrob Chemother. 2014. PMID: 24833752

7

Silk Hydrogel Electrostatically Functionalized with a Polycationic Antimicrobial Peptide: Molecular Interactions, Gel Properties, and Antimicrobial Activity.

Aye SSS, Zhang ZH, Yu X, Yu H, Ma WD, Yang K, Liu X, Li J, Li JL. Aye SSS, et al. Langmuir. 2022 Jan 11;38(1):50-61. doi: 10.1021/acs.langmuir.1c01312. Epub 2021 Dec 28. Langmuir. 2022. PMID: 34963282

8

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation.

Hickey SM, Ashton TD, White JM, Li J, Nation RL, Yu HY, Elliott AG, Butler MS, Huang JX, Cooper MA, Pfeffer FM. Hickey SM, et al. Among authors: yu hy. RSC Adv. 2015;5:28582-28596. doi: 10.1039/C5RA03321G. RSC Adv. 2015. PMID: 26251697 Free PMC article.

9

Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane.

Hickey SM, Ashton TD, Boer G, Bader CA, Thomas M, Elliott AG, Schmuck C, Yu HY, Li J, Nation RL, Cooper MA, Plush SE, Brooks DA, Pfeffer FM. Hickey SM, et al. Among authors: yu hy. Eur J Med Chem. 2018 Dec 5;160:9-22. doi: 10.1016/j.ejmech.2018.09.072. Epub 2018 Oct 3. Eur J Med Chem. 2018. PMID: 30316060 Free PMC article.

10

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents.

Hickey SM, Ashton TD, Khosa SK, Robson RN, White JM, Li J, Nation RL, Yu HY, Elliott AG, Butler MS, Huang JX, Cooper MA, Pfeffer FM. Hickey SM, et al. Among authors: yu hy. Org Biomol Chem. 2015 Jun 14;13(22):6225-41. doi: 10.1039/c5ob00621j. Org Biomol Chem. 2015. PMID: 25958967

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