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Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation.
De Lombaerde E, Cui X, Chen Y, Zhong Z, Deckers J, Mencarelli G, Opsomer L, Wang H, De Baere J, Lienenklaus S, Lambrecht BN, Sanders NN, De Geest BG. De Lombaerde E, et al. Among authors: chen y. ACS Nano. 2024 Oct 15;18(41):28311-28324. doi: 10.1021/acsnano.4c09677. Epub 2024 Oct 1. ACS Nano. 2024. PMID: 39352021
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles.
Wang B, Van Herck S, Chen Y, Bai X, Zhong Z, Deswarte K, Lambrecht BN, Sanders NN, Lienenklaus S, Scheeren HW, David SA, Kiessling F, Lammers T, De Geest BG, Shi Y. Wang B, et al. Among authors: chen y. J Am Chem Soc. 2020 Jul 15;142(28):12133-12139. doi: 10.1021/jacs.0c01928. Epub 2020 Jun 30. J Am Chem Soc. 2020. PMID: 32524819 Free PMC article.
Lipid-Polyglutamate Nanoparticle Vaccine Platform.
Van Lysebetten D, Malfanti A, Deswarte K, Koynov K, Golba B, Ye T, Zhong Z, Kasmi S, Lamoot A, Chen Y, Van Herck S, Lambrecht BN, Sanders NN, Lienenklaus S, David SA, Vicent MJ, De Koker S, De Geest BG. Van Lysebetten D, et al. Among authors: chen y. ACS Appl Mater Interfaces. 2021 Feb 10;13(5):6011-6022. doi: 10.1021/acsami.0c20607. Epub 2021 Jan 28. ACS Appl Mater Interfaces. 2021. PMID: 33507728 Free PMC article.
Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions.
Braet H, Fransen PP, Chen Y, Van Herck S, Mariën R, Vanhoorne V, Ceelen W, Madder A, Ballet S, Hoogenboom R, De Geest B, Hoorens A, Dankers PYW, De Smedt SC, Remaut K. Braet H, et al. Among authors: chen y. J Control Release. 2023 Oct;362:138-150. doi: 10.1016/j.jconrel.2023.08.042. Epub 2023 Aug 31. J Control Release. 2023. PMID: 37619864
Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue.
Zhong Z, Chen Y, Deswarte K, Lauwers H, De Lombaerde E, Cui X, Van Herck S, Ye T, Gontsarik M, Lienenklaus S, Sanders NN, Lambrecht BN, De Koker S, De Geest BG. Zhong Z, et al. Among authors: chen y. Adv Healthc Mater. 2023 Dec;12(32):e2301687. doi: 10.1002/adhm.202301687. Epub 2023 Oct 11. Adv Healthc Mater. 2023. PMID: 37772637
177,065 results
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