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Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.
Zhu X, Farsh T, Vis D, Yu I, Li H, Liu T, Sjöström M, Shrestha R, Kneppers J, Severson T, Zhang M, Lundberg A, Moreno Rodriguez T, Weinstein AS, Foye A, Mehra N, Aggarwal RR, Bergman AM, Small EJ, Lack NA, Zwart W, Quigley DA, van der Heijden MS, Feng FY. Zhu X, et al. J Clin Invest. 2024 Aug 13;134(19):e178604. doi: 10.1172/JCI178604. J Clin Invest. 2024. PMID: 39352383 Free PMC article.
A prostate cancer gastrointestinal transcriptional phenotype may be associated with diminished response to AR-targeted therapy.
Subramanian A, Zhang M, Sharifi M, Moreno-Rodriguez T, Feng E, Rydzewski NR, Shrestha R, Zhu X, Zhao SG, Aggarwal R, Small EJ, Ding CC, Quigley DA, Sjöström M. Subramanian A, et al. Among authors: zhu x. bioRxiv [Preprint]. 2024 Jun 3:2024.06.02.595931. doi: 10.1101/2024.06.02.595931. bioRxiv. 2024. PMID: 38895460 Free PMC article. Preprint.
Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint Inhibitors or Enfortumab Vedotin.
Jindal T, Zhang L, Deshmukh P, Reyes K, Chan E, Kumar V, Zhu X, Maldonado E, Feng S, Johnson M, Angelidakis A, Kwon D, Desai A, Borno HT, Bose R, Wong A, Hong J, Carroll P, Meng M, Porten S, Aggarwal R, Small EJ, Fong L, Chou J, Friedlander T, de Kouchkovsky I, Koshkin VS. Jindal T, et al. Among authors: zhu x. Clin Genitourin Cancer. 2023 Oct;21(5):e394-e404. doi: 10.1016/j.clgc.2023.05.007. Epub 2023 May 17. Clin Genitourin Cancer. 2023. PMID: 37316414 Free article.
Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer.
Jindal T, Zhu X, Bose R, Kumar V, Maldonado E, Deshmukh P, Shipp C, Feng S, Johnson MS, Angelidakis A, Kwon D, Borno HT, de Kouchkovsky I, Desai A, Aggarwal R, Fong L, Small EJ, Wong A, Porten S, Chou J, Friedlander T, Koshkin VS. Jindal T, et al. Among authors: zhu x. Front Oncol. 2023 Apr 5;13:1161089. doi: 10.3389/fonc.2023.1161089. eCollection 2023. Front Oncol. 2023. PMID: 37091148 Free PMC article.
Diverse ancestry GWAS for advanced age-related macular degeneration in TOPMed-imputed and Ophthalmologically-confirmed 16,108 cases and 18,038 controls.
Gorski M, Grunin M, Herold JM, Fröhlich B, Behr M, Wheeler N, Bush WS, Song YE, Zhu X, Blanton SH, Pericak-Vance MA, Heid IM, Haines JL; International Age-related Macular Degeneration Genomics Consortium. Gorski M, et al. Among authors: zhu x. medRxiv [Preprint]. 2024 Nov 11:2024.11.08.24316962. doi: 10.1101/2024.11.08.24316962. medRxiv. 2024. PMID: 39606372 Free PMC article. Preprint.
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