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Page 1
Endothelial cell-specific progerin expression does not cause cardiovascular alterations and premature death.
Benedicto I, Hamczyk MR, Nevado RM, Barettino A, Carmona RM, Espinós-Estévez C, Gonzalo P, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Dorado B, Andrés V. Benedicto I, et al. Among authors: barettino a. Aging Cell. 2024 Oct 31:e14389. doi: 10.1111/acel.14389. Online ahead of print. Aging Cell. 2024. PMID: 39479939 Free article.
Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome.
Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I, Andrés V. Barettino A, et al. J Clin Invest. 2024 Oct 1;134(22):e173448. doi: 10.1172/JCI173448. J Clin Invest. 2024. PMID: 39352768 Free PMC article.
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Benedicto I, et al. Among authors: barettino a. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2400752121. doi: 10.1073/pnas.2400752121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648484 Free PMC article.
Biological Versus Chronological Aging: JACC Focus Seminar.
Hamczyk MR, Nevado RM, Barettino A, Fuster V, Andrés V. Hamczyk MR, et al. Among authors: barettino a. J Am Coll Cardiol. 2020 Mar 3;75(8):919-930. doi: 10.1016/j.jacc.2019.11.062. J Am Coll Cardiol. 2020. PMID: 32130928 Free article. Review.
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome.
Dorado B, Pløen GG, Barettino A, Macías A, Gonzalo P, Andrés-Manzano MJ, González-Gómez C, Galán-Arriola C, Alfonso JM, Lobo M, López-Martín GJ, Molina A, Sánchez-Sánchez R, Gadea J, Sánchez-González J, Liu Y, Callesen H, Filgueiras-Rama D, Ibáñez B, Sørensen CB, Andrés V. Dorado B, et al. Among authors: barettino a. Cell Discov. 2019 Mar 19;5:16. doi: 10.1038/s41421-019-0084-z. eCollection 2019. Cell Discov. 2019. PMID: 30911407 Free PMC article.
Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging.
Borras C, Abdelaziz KM, Gambini J, Serna E, Inglés M, de la Fuente M, Garcia I, Matheu A, Sanchís P, Belenguer A, Errigo A, Avellana JA, Barettino A, Lloret-Fernández C, Flames N, Pes G, Rodriguez-Mañas L, Viña J. Borras C, et al. Among authors: barettino a. Aging (Albany NY). 2016 Oct 28;8(12):3185-3208. doi: 10.18632/aging.101078. Aging (Albany NY). 2016. PMID: 27794564 Free PMC article.