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Page 1
Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7.
Doyle CA, Busey GW, Iobst WH, Kiessling V, Renken C, Doppalapudi H, Stremska ME, Manjegowda MC, Arish M, Wang W, Naphade S, Kennedy J, Bloyet LM, Thompson CE, Rothlauf PW, Stipes EJ, Whelan SPJ, Tamm LK, Kreutzberger AJB, Sun J, Desai BN. Doyle CA, et al. Among authors: stremska me. Nat Commun. 2024 Oct 1;15(1):8479. doi: 10.1038/s41467-024-52773-w. Nat Commun. 2024. PMID: 39353909 Free PMC article.
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Schappe MS, Szteyn K, Stremska ME, Mendu SK, Downs TK, Seegren PV, Mahoney MA, Dixit S, Krupa JK, Stipes EJ, Rogers JS, Adamson SE, Leitinger N, Desai BN. Schappe MS, et al. Among authors: stremska me. Immunity. 2018 Jan 16;48(1):59-74.e5. doi: 10.1016/j.immuni.2017.11.026. Immunity. 2018. PMID: 29343440 Free PMC article.
Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing.
Seegren PV, Downs TK, Stremska ME, Harper LR, Cao R, Olson RJ, Upchurch CM, Doyle CA, Kennedy J, Stipes EL, Leitinger N, Periasamy A, Desai BN. Seegren PV, et al. Among authors: stremska me. Cell Rep. 2020 Nov 24;33(8):108411. doi: 10.1016/j.celrep.2020.108411. Cell Rep. 2020. PMID: 33238121 Free PMC article.
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release.
Tufan T, Comertpay G, Villani A, Nelson GM, Terekhova M, Kelley S, Zakharov P, Ellison RM, Shpynov O, Raymond M, Sun J, Chen Y, Bockelmann E, Stremska M, Peterson LW, Boeckaerts L, Goldman SR, Etchegaray JI, Artyomov MN, Peri F, Ravichandran KS. Tufan T, et al. Nature. 2024 Apr;628(8007):408-415. doi: 10.1038/s41586-024-07172-y. Epub 2024 Mar 13. Nature. 2024. PMID: 38480883
Phagocytosis in the retina promotes local insulin production in the eye.
Iker Etchegaray J, Kelley S, Penberthy K, Karvelyte L, Nagasaka Y, Gasperino S, Paul S, Seshadri V, Raymond M, Marco AR, Pinney J, Stremska M, Barron B, Lucas C, Wase N, Fan Y, Unanue E, Kundu B, Burstyn-Cohen T, Perry J, Ambati J, Ravichandran KS. Iker Etchegaray J, et al. Nat Metab. 2023 Feb;5(2):207-218. doi: 10.1038/s42255-022-00728-0. Epub 2023 Feb 2. Nat Metab. 2023. PMID: 36732622 Free PMC article.
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