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Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist.
Fontaine T, Busch A, Laeremans T, De Cesco S, Liang YL, Jaakola VP, Sands Z, Triest S, Masiulis S, Dekeyzer L, Samyn N, Loeys N, Perneel L, Debaere M, Martini M, Vantieghem C, Virmani R, Skieterska K, Staelens S, Barroco R, Van Roy M, Menet C. Fontaine T, et al. Among authors: laeremans t. Nat Commun. 2024 Oct 1;15(1):7029. doi: 10.1038/s41467-024-50827-7. Nat Commun. 2024. PMID: 39353917 Free PMC article.
Structural Basis of μ-Opioid Receptor-Targeting by a Nanobody Antagonist.
Yu J, Kumar A, Zhang X, Martin C, Raia P, Koehl A, Laeremans T, Steyaert J, Manglik A, Ballet S, Boland A, Stoeber M. Yu J, et al. Among authors: laeremans t. bioRxiv [Preprint]. 2023 Dec 7:2023.12.06.570395. doi: 10.1101/2023.12.06.570395. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 9;15(1):8687. doi: 10.1038/s41467-024-52947-6 PMID: 38106026 Free PMC article. Updated. Preprint.
The role of mRNA-galsomes and LNPs in enhancing HIV-specific T cell responses across various lymphoid organs.
D'haese S, den Roover S, Verbeke R, Aernout I, Meulewater S, Cosyns J, Meert J, Vanbellingen S, Laeremans T, Lentacker I, Aerts JL. D'haese S, et al. Among authors: laeremans t. Mol Ther Nucleic Acids. 2024 Oct 28;35(4):102372. doi: 10.1016/j.omtn.2024.102372. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39618822 Free PMC article.
Structural basis of μ-opioid receptor targeting by a nanobody antagonist.
Yu J, Kumar A, Zhang X, Martin C, Van Holsbeeck K, Raia P, Koehl A, Laeremans T, Steyaert J, Manglik A, Ballet S, Boland A, Stoeber M. Yu J, et al. Among authors: laeremans t. Nat Commun. 2024 Oct 9;15(1):8687. doi: 10.1038/s41467-024-52947-6. Nat Commun. 2024. PMID: 39384768 Free PMC article.
46 results