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RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis.
Zou Z, Dou X, Li Y, Zhang Z, Wang J, Gao B, Xiao Y, Wang Y, Zhao L, Sun C, Liu Q, Yu X, Wang H, Hong J, Dai Q, Yang FC, Xu M, He C. Zou Z, et al. Among authors: yang fc. Nature. 2024 Oct;634(8035):986-994. doi: 10.1038/s41586-024-07969-x. Epub 2024 Oct 2. Nature. 2024. PMID: 39358506 Free PMC article.
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Pan F, Wingo TS, Zhao Z, Gao R, Makishima H, Qu G, Lin L, Yu M, Ortega JR, Wang J, Nazha A, Chen L, Yao B, Liu C, Chen S, Weeks O, Ni H, Phillips BL, Huang S, Wang J, He C, Li GM, Radivoyevitch T, Aifantis I, Maciejewski JP, Yang FC, Jin P, Xu M. Pan F, et al. Among authors: yang fc. Nat Commun. 2017 Apr 25;8:15102. doi: 10.1038/ncomms15102. Nat Commun. 2017. PMID: 28440315 Free PMC article.
INTS11 regulates hematopoiesis by promoting PRC2 function.
Zhang P, Sui P, Chen S, Guo Y, Li Y, Ge G, Zhu G, Yang H, Rogers CM, Sung P, Nimer SD, Xu M, Yang FC. Zhang P, et al. Among authors: yang fc, yang h. Sci Adv. 2021 Sep 3;7(36):eabh1684. doi: 10.1126/sciadv.abh1684. Epub 2021 Sep 1. Sci Adv. 2021. PMID: 34516911 Free PMC article.
Loss of Asxl2 leads to myeloid malignancies in mice.
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, Williams S, Chen X, Wang QT, Nimer SD, Yu P, Wang QF, Xu M, Yang FC. Li J, et al. Among authors: yang fc, yang h. Nat Commun. 2017 Jun 8;8:15456. doi: 10.1038/ncomms15456. Nat Commun. 2017. PMID: 28593990 Free PMC article.
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, Lin L, Street C, Wunderlich M, Dawlaty M, Neilly MB, Jaenisch R, Yang FC, Mulloy JC, Jin P, Liu PP, Rowley JD, Xu M, He C, Chen J. Huang H, et al. Among authors: yang fc. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11994-9. doi: 10.1073/pnas.1310656110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818607 Free PMC article.
SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis.
Sui P, Ge G, Chen S, Bai J, Rubalcava IP, Yang H, Guo Y, Zhang P, Li Y, Medina EA, Xu M, Abdel-Wahab O, Bradley R, Yang FC. Sui P, et al. Among authors: yang fc, yang h. Leukemia. 2024 Feb;38(2):408-411. doi: 10.1038/s41375-023-02094-6. Epub 2023 Nov 28. Leukemia. 2024. PMID: 38017104 Free PMC article. No abstract available.
462 results