Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

25 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Relocalizing transcriptional kinases to activate apoptosis.
Sarott RC, Gourisankar S, Karim B, Nettles S, Yang H, Dwyer BG, Simanauskaite JM, Tse J, Abuzaid H, Krokhotin A, Zhang T, Hinshaw SM, Green MR, Crabtree GR, Gray NS. Sarott RC, et al. Among authors: hinshaw sm. Science. 2024 Oct 4;386(6717):eadl5361. doi: 10.1126/science.adl5361. Epub 2024 Oct 4. Science. 2024. PMID: 39361741
Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors.
Lu W, Fan M, Ji W, Tse J, You I, Ficarro SB, Tavares I, Che J, Kim AY, Zhu X, Boghossian A, Rees MG, Ronan MM, Roth JA, Hinshaw SM, Nabet B, Corsello SM, Kwiatkowski N, Marto JA, Zhang T, Gray NS. Lu W, et al. Among authors: hinshaw sm. J Med Chem. 2023 Apr 13;66(7):4617-4632. doi: 10.1021/acs.jmedchem.2c01548. Epub 2023 Mar 22. J Med Chem. 2023. PMID: 36946421 Free PMC article.
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.
Sarott RC, You I, Li YD, Toenjes ST, Donovan KA, Seo P, Ordonez M, Byun WS, Hassan MM, Wachter F, Chouchani ET, Słabicki M, Fischer ES, Ebert BL, Hinshaw SM, Gray NS. Sarott RC, et al. Among authors: hinshaw sm. J Am Chem Soc. 2023 Oct 11;145(40):21937-21944. doi: 10.1021/jacs.3c06622. Epub 2023 Sep 28. J Am Chem Soc. 2023. PMID: 37767920
Borrowing Transcriptional Kinases to Activate Apoptosis.
Sarott R, Gourisankar S, Karim B, Nettles S, Yang H, Dwyer BG, Simanauskaite JM, Tse J, Abuzaid H, Krokhotin A, Zhang T, Hinshaw SM, Green MR, Crabtree GR, Gray NS. Sarott R, et al. Among authors: hinshaw sm. bioRxiv [Preprint]. 2023 Oct 25:2023.10.23.563687. doi: 10.1101/2023.10.23.563687. bioRxiv. 2023. Update in: Science. 2024 Oct 4;386(6717):eadl5361. doi: 10.1126/science.adl5361 PMID: 37961702 Free PMC article. Updated. Preprint.
Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library.
Razumkov H, Jiang Z, Baek K, You I, Geng Q, Donovan KA, Tang MT, Metivier RJ, Mageed N, Seo P, Li Z, Byun WS, Hinshaw SM, Sarott RC, Fischer ES, Gray NS. Razumkov H, et al. Among authors: hinshaw sm. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550. doi: 10.1101/2024.05.04.592550. bioRxiv. 2024. Update in: J Am Chem Soc. 2024 Nov 20;146(46):31433-31443. doi: 10.1021/jacs.4c06127 PMID: 38746375 Free PMC article. Updated. Preprint.
Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7).
Ji W, Du G, Jiang J, Lu W, Mills CE, Yuan L, Jiang F, He Z, Bradshaw GA, Chung M, Jiang Z, Byun WS, Hinshaw SM, Zhang T, Gray NS. Ji W, et al. Among authors: hinshaw sm. Eur J Med Chem. 2024 Oct 5;276:116613. doi: 10.1016/j.ejmech.2024.116613. Epub 2024 Jun 27. Eur J Med Chem. 2024. PMID: 39004018
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET. Liu W, et al. Among authors: hinshaw sm. Nature. 2023 Apr;616(7958):790-797. doi: 10.1038/s41586-023-05939-3. Epub 2023 Mar 15. Nature. 2023. PMID: 36921622
25 results