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The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19.
Gottlieb RL, Clement M, Cook P, Deveikis A, Foong KS, Robinson P, Slim J, Spak CW, Buelens A, Callewaert K, De Meyer S, Mo WL, Verbrugge I, Van Wesenbeeck L, Zhuang Y, Chien JW, Opsomer M, Van Landuyt E. Gottlieb RL, et al. Among authors: van wesenbeeck l. J Infect. 2024 Oct;89(4):106241. doi: 10.1016/j.jinf.2024.106241. Epub 2024 Sep 2. J Infect. 2024. PMID: 39182655 Free article. Clinical Trial.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Goethals O, Kaptein SJF, Kesteleyn B, Bonfanti JF, Van Wesenbeeck L, Bardiot D, Verschoor EJ, Verstrepen BE, Fagrouch Z, Putnak JR, Kiemel D, Ackaert O, Straetemans R, Lachau-Durand S, Geluykens P, Crabbe M, Thys K, Stoops B, Lenz O, Tambuyzer L, De Meyer S, Dallmeier K, McCracken MK, Gromowski GD, Rutvisuttinunt W, Jarman RG, Karasavvas N, Touret F, Querat G, de Lamballerie X, Chatel-Chaix L, Milligan GN, Beasley DWC, Bourne N, Barrett ADT, Marchand A, Jonckers THM, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Bogers WM, Neyts J, Van Loock M. Goethals O, et al. Among authors: van wesenbeeck l. Nature. 2023 Mar;615(7953):678-686. doi: 10.1038/s41586-023-05790-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922586 Free PMC article.
A phylogenetic study of dengue virus in urban Vietnam shows long-term persistence of endemic strains.
Ashall J, Shah S, Biggs JR, Chang JR, Jafari Y, Brady OJ, Mai HK, Lien LT, Do Thai H, Nguyen HAT, Anh DD, Iwasaki C, Kitamura N, Van Loock M, Herrera-Taracena G, Rasschaert F, Van Wesenbeeck L, Yoshida LM, Hafalla JCR, Hue S, Hibberd ML. Ashall J, et al. Among authors: van wesenbeeck l. Virus Evol. 2023 Feb 16;9(1):vead012. doi: 10.1093/ve/vead012. eCollection 2023. Virus Evol. 2023. PMID: 36926448 Free PMC article.
Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers.
Bhandari YR, Krishna V, Powers R, Parmar S, Thursby SJ, Gupta E, Kulak O, Gokare P, Reumers J, Van Wesenbeeck L, Bachman KE, Baylin SB, Easwaran H. Bhandari YR, et al. Among authors: van wesenbeeck l. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2301536120. doi: 10.1073/pnas.2301536120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487069 Free PMC article.
Evolution of inflammation and immunity in a dengue virus 1 human infection model.
Waickman AT, Lu JQ, Fang H, Waldran MJ, Gebo C, Currier JR, Ware L, Van Wesenbeeck L, Verpoorten N, Lenz O, Tambuyzer L, Herrera-Taracena G, Van Loock M, Endy TP, Thomas SJ. Waickman AT, et al. Among authors: van wesenbeeck l. Sci Transl Med. 2022 Oct 26;14(668):eabo5019. doi: 10.1126/scitranslmed.abo5019. Epub 2022 Oct 26. Sci Transl Med. 2022. PMID: 36288280
Combining rapid diagnostic tests to estimate primary and post-primary dengue immune status at the point of care.
Biggs JR, Sy AK, Ashall J, Santoso MS, Brady OJ, Reyes MAJ, Quinones MA, Jones-Warner W, Tandoc AO, Sucaldito NL, Mai HK, Lien LT, Thai HD, Nguyen HAT, Anh DD, Iwasaki C, Kitamura N, Van Loock M, Herrera-Taracena G, Menten J, Rasschaert F, Van Wesenbeeck L, Masyeni S, Haryanto S, Yohan B, Cutiongco-de la Paz E, Yoshida LM, Hue S, Rosario Z Capeding M, Padilla CD, Sasmono RT, Hafalla JCR, Hibberd ML. Biggs JR, et al. Among authors: van wesenbeeck l. PLoS Negl Trop Dis. 2022 May 4;16(5):e0010365. doi: 10.1371/journal.pntd.0010365. eCollection 2022 May. PLoS Negl Trop Dis. 2022. PMID: 35507552 Free PMC article.
38 results