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Page 1
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases.
Kieliszek AM, Mobilio D, Bassey-Archibong BI, Johnson JW, Piotrowski ML, de Araujo ED, Sedighi A, Aghaei N, Escudero L, Ang P, Gwynne WD, Zhang C, Quaile A, McKenna D, Subapanditha M, Tokar T, Vaseem Shaikh M, Zhai K, Chafe SC, Gunning PT, Montenegro-Burke JR, Venugopal C, Magolan J, Singh SK. Kieliszek AM, et al. Cell Rep Med. 2024 Oct 15;5(10):101755. doi: 10.1016/j.xcrm.2024.101755. Epub 2024 Oct 4. Cell Rep Med. 2024. PMID: 39366383 Free PMC article.
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells.
Chokshi CR, Shaikh MV, Brakel B, Rossotti MA, Tieu D, Maich W, Anand A, Chafe SC, Zhai K, Suk Y, Kieliszek AM, Miletic P, Mikolajewicz N, Chen D, McNicol JD, Chan K, Tong AHY, Kuhlmann L, Liu L, Alizada Z, Mobilio D, Tatari N, Savage N, Aghaei N, Grewal S, Puri A, Subapanditha M, McKenna D, Ignatchenko V, Salamoun JM, Kwiecien JM, Wipf P, Sharlow ER, Provias JP, Lu JQ, Lazo JS, Kislinger T, Lu Y, Brown KR, Venugopal C, Henry KA, Moffat J, Singh SK. Chokshi CR, et al. Among authors: kieliszek am. Nat Med. 2024 Oct;30(10):2936-2946. doi: 10.1038/s41591-024-03138-9. Epub 2024 Aug 2. Nat Med. 2024. PMID: 39095594
An HLA-G/SPAG9/STAT3 axis promotes brain metastases.
Bassey-Archibong BI, Rajendra Chokshi C, Aghaei N, Kieliszek AM, Tatari N, McKenna D, Singh M, Kalpana Subapanditha M, Parmar A, Mobilio D, Savage N, Lam F, Tokar T, Provias J, Lu Y, Chafe SC, Swanton C, Hynds RE, Venugopal C, Singh SK. Bassey-Archibong BI, et al. Among authors: kieliszek am. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2205247120. doi: 10.1073/pnas.2205247120. Epub 2023 Feb 13. Proc Natl Acad Sci U S A. 2023. PMID: 36780531 Free PMC article.
Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences.
Skinnider MA, Johnston CW, Gunabalasingam M, Merwin NJ, Kieliszek AM, MacLellan RJ, Li H, Ranieri MRM, Webster ALH, Cao MPT, Pfeifle A, Spencer N, To QH, Wallace DP, Dejong CA, Magarvey NA. Skinnider MA, et al. Among authors: kieliszek am. Nat Commun. 2020 Nov 27;11(1):6058. doi: 10.1038/s41467-020-19986-1. Nat Commun. 2020. PMID: 33247171 Free PMC article.