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Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses.
Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Bobilev E, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Liu F, Chen J, Wu CJ, Barbie D, Li J, Romee R. Yang S, et al. Among authors: marquez pellegrin v. Nat Biotechnol. 2024 Oct 4. doi: 10.1038/s41587-024-02418-6. Online ahead of print. Nat Biotechnol. 2024. PMID: 39367093
Nonpathogenic E. coli engineered to surface display cytokines as a new platform for immunotherapy.
Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Chen J, Wu CJ, Barbie D, Li J, Romee R. Yang S, et al. Among authors: marquez pellegrin v. Res Sq [Preprint]. 2024 Mar 22:rs.3.rs-4031911. doi: 10.21203/rs.3.rs-4031911/v1. Res Sq. 2024. Update in: Nat Biotechnol. 2024 Oct 4. doi: 10.1038/s41587-024-02418-6 PMID: 38562821 Free PMC article. Updated. Preprint.