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Page 1
Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib.
Zhang X, Rameika N, Zhong L, Rendo V, Veanes M, Kundu S, Nuciforo S, Dupuis J, Al Azhar M, Tsiara I, Seeburger P, Al Nassralla S, Ljungström V, Svensson R, Stoimenov I, Artursson P, Heim MH, Globisch D, Sjöblom T. Zhang X, et al. Among authors: ljungstrom v. EBioMedicine. 2024 Nov;109:105368. doi: 10.1016/j.ebiom.2024.105368. Epub 2024 Oct 4. EBioMedicine. 2024. PMID: 39368455 Free PMC article.
The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia.
Hägerstrand D, Oder B, Cortese D, Qu Y, Binzer-Panchal A, Österholm C, Del Peso Santos T, Rabbani L, Asl HF, Skaftason A, Ljungström V, Lundholm A, Koutroumani M, Haider Z, Jylhä C, Mollstedt J, Mansouri L, Plevova K, Agathangelidis A, Scarfò L, Armand M, Muggen AF, Kay NE, Shanafelt T, Rossi D, Orre LM, Pospisilova S, Barylyuk K, Davi F, Vesterlund M, Langerak AW, Lehtiö J, Ghia P, Stamatopoulos K, Sutton LA, Rosenquist R. Hägerstrand D, et al. Among authors: ljungstrom v. Leukemia. 2024 Nov;38(11):2429-2442. doi: 10.1038/s41375-024-02379-4. Epub 2024 Sep 11. Leukemia. 2024. PMID: 39261602 Free PMC article.
Prognostic genome and transcriptome signatures in colorectal cancers.
Nunes L, Li F, Wu M, Luo T, Hammarström K, Torell E, Ljuslinder I, Mezheyeuski A, Edqvist PH, Löfgren-Burström A, Zingmark C, Edin S, Larsson C, Mathot L, Osterman E, Osterlund E, Ljungström V, Neves I, Yacoub N, Guðnadóttir U, Birgisson H, Enblad M, Ponten F, Palmqvist R, Xu X, Uhlén M, Wu K, Glimelius B, Lin C, Sjöblom T. Nunes L, et al. Among authors: ljungstrom v. Nature. 2024 Sep;633(8028):137-146. doi: 10.1038/s41586-024-07769-3. Epub 2024 Aug 7. Nature. 2024. PMID: 39112715 Free PMC article.
Accurate and sensitive mutational signature analysis with MuSiCal.
Jin H, Gulhan DC, Geiger B, Ben-Isvy D, Geng D, Ljungström V, Park PJ. Jin H, et al. Among authors: ljungstrom v. Nat Genet. 2024 Mar;56(3):541-552. doi: 10.1038/s41588-024-01659-0. Epub 2024 Feb 15. Nat Genet. 2024. PMID: 38361034 Free PMC article.
Predicting response to immune checkpoint blockade therapy among mismatch repair-deficient patients using mutational signatures.
Gulhan DC, Viswanadham V, Muyas F, Jin H, Foote MB, Lee JJ, Barras D, Jung YL, Ljungstrom V, Rousseau B, Galor A, Diplas BH, Maron SB, Cleary JM, Cortés-Ciriano I, Park PJ. Gulhan DC, et al. Among authors: ljungstrom v. medRxiv [Preprint]. 2024 Jan 21:2024.01.19.24301236. doi: 10.1101/2024.01.19.24301236. medRxiv. 2024. PMID: 38293061 Free PMC article. Preprint.
A pan-tissue survey of mosaic chromosomal alterations in 948 individuals.
Gao T, Kastriti ME, Ljungström V, Heinzel A, Tischler AS, Oberbauer R, Loh PR, Adameyko I, Park PJ, Kharchenko PV. Gao T, et al. Among authors: ljungstrom v. Nat Genet. 2023 Nov;55(11):1901-1911. doi: 10.1038/s41588-023-01537-1. Epub 2023 Oct 30. Nat Genet. 2023. PMID: 37904053 Free PMC article.
ERα-associated translocations underlie oncogene amplifications in breast cancer.
Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ. Lee JJ, et al. Among authors: ljungstrom v. Nature. 2023 Jun;618(7967):1024-1032. doi: 10.1038/s41586-023-06057-w. Epub 2023 May 17. Nature. 2023. PMID: 37198482 Free PMC article.
BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib.
Bonfiglio S, Sutton LA, Ljungström V, Capasso A, Pandzic T, Weström S, Foroughi-Asl H, Skaftason A, Gellerbring A, Lyander A, Gandini F, Gaidano G, Trentin L, Bonello L, Reda G, Bödör C, Stavroyianni N, Tam CS, Marasca R, Forconi F, Panayiotidis P, Ringshausen I, Jaksic O, Frustaci AM, Iyengar S, Coscia M, Mulligan SP, Ysebaert L, Strugov V, Pavlovsky C, Walewska R, Österborg A, Cortese D, Ranghetti P, Baliakas P, Stamatopoulos K, Scarfò L, Rosenquist R, Ghia P. Bonfiglio S, et al. Among authors: ljungstrom v. Blood Adv. 2023 Jun 27;7(12):2794-2806. doi: 10.1182/bloodadvances.2022008821. Blood Adv. 2023. PMID: 36696464 Free PMC article.
Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting.
Pandzic T, Ladenvall C, Engvall M, Mattsson M, Hermanson M, Cavelier L, Ljungström V, Baliakas P. Pandzic T, et al. Among authors: ljungstrom v. Hemasphere. 2022 Aug 2;6(8):e761. doi: 10.1097/HS9.0000000000000761. eCollection 2022 Aug. Hemasphere. 2022. PMID: 35935605 Free PMC article.
43 results