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Page 1
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity.
Pigoni M, Uzquiano A, Paulsen B, Kedaigle AJ, Yang SM, Symvoulidis P, Adiconis X, Velasco S, Sartore R, Kim K, Tucewicz A, Tropp SY, Tsafou K, Jin X, Barrett L, Chen F, Boyden ES, Regev A, Levin JZ, Arlotta P. Pigoni M, et al. Among authors: arlotta p. Hum Mol Genet. 2023 Sep 5;32(18):2773-2786. doi: 10.1093/hmg/ddad107. Hum Mol Genet. 2023. PMID: 37384417 Free PMC article.
Autism genes converge on asynchronous development of shared neuron classes.
Paulsen B, Velasco S, Kedaigle AJ, Pigoni M, Quadrato G, Deo AJ, Adiconis X, Uzquiano A, Sartore R, Yang SM, Simmons SK, Symvoulidis P, Kim K, Tsafou K, Podury A, Abbate C, Tucewicz A, Smith SN, Albanese A, Barrett L, Sanjana NE, Shi X, Chung K, Lage K, Boyden ES, Regev A, Levin JZ, Arlotta P. Paulsen B, et al. Among authors: arlotta p. Nature. 2022 Feb;602(7896):268-273. doi: 10.1038/s41586-021-04358-6. Epub 2022 Feb 2. Nature. 2022. PMID: 35110736 Free PMC article.
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.
Uzquiano A, Kedaigle AJ, Pigoni M, Paulsen B, Adiconis X, Kim K, Faits T, Nagaraja S, Antón-Bolaños N, Gerhardinger C, Tucewicz A, Murray E, Jin X, Buenrostro J, Chen F, Velasco S, Regev A, Levin JZ, Arlotta P. Uzquiano A, et al. Among authors: arlotta p. Cell. 2022 Sep 29;185(20):3770-3788.e27. doi: 10.1016/j.cell.2022.09.010. Cell. 2022. PMID: 36179669 Free PMC article.
Multiscale 3D phenotyping of human cerebral organoids.
Albanese A, Swaney JM, Yun DH, Evans NB, Antonucci JM, Velasco S, Sohn CH, Arlotta P, Gehrke L, Chung K. Albanese A, et al. Among authors: arlotta p. Sci Rep. 2020 Dec 8;10(1):21487. doi: 10.1038/s41598-020-78130-7. Sci Rep. 2020. PMID: 33293587 Free PMC article.
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers.
Antón-Bolaños N, Faravelli I, Faits T, Andreadis S, Kastli R, Trattaro S, Adiconis X, Wei A, Sampath Kumar A, Di Bella DJ, Tegtmeyer M, Nehme R, Levin JZ, Regev A, Arlotta P. Antón-Bolaños N, et al. Among authors: arlotta p. Nature. 2024 Jul;631(8019):142-149. doi: 10.1038/s41586-024-07578-8. Epub 2024 Jun 26. Nature. 2024. PMID: 38926573
Molecular logic of cellular diversification in the mouse cerebral cortex.
Di Bella DJ, Habibi E, Stickels RR, Scalia G, Brown J, Yadollahpour P, Yang SM, Abbate C, Biancalani T, Macosko EZ, Chen F, Regev A, Arlotta P. Di Bella DJ, et al. Among authors: arlotta p. Nature. 2021 Jul;595(7868):554-559. doi: 10.1038/s41586-021-03670-5. Epub 2021 Jun 23. Nature. 2021. PMID: 34163074 Free PMC article.
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