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Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism.
Durumutla HB, Prabakaran AD, Soussi FEA, Akinborewa O, Latimer H, McFarland K, Piczer K, Werbrich C, Jain MK, Haldar SM, Quattrocelli M. Durumutla HB, et al. Among authors: mcfarland k. bioRxiv [Preprint]. 2024 Sep 11:2023.12.18.572210. doi: 10.1101/2023.12.18.572210. bioRxiv. 2024. PMID: 38187555 Free PMC article. Preprint.
Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation.
Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Blair NS, Millay DP, Prideaux B, Finck BN, Quattrocelli M. Prabakaran AD, et al. Among authors: mcfarland k. bioRxiv [Preprint]. 2023 Oct 19:2023.10.16.562573. doi: 10.1101/2023.10.16.562573. bioRxiv. 2023. PMID: 37905062 Free PMC article. Preprint.
The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.
Prabakaran AD, Chung HJ, McFarland K, Govindarajan T, El Abdellaoui Soussi F, Durumutla HB, Villa C, Piczer K, Latimer H, Werbrich C, Akinborewa O, Horning R, Quattrocelli M. Prabakaran AD, et al. Among authors: mcfarland k. bioRxiv [Preprint]. 2024 Mar 31:2024.03.28.586997. doi: 10.1101/2024.03.28.586997. bioRxiv. 2024. PMID: 38585940 Free PMC article. Preprint.
Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1α/Lipin1 axis in an aging-related sarcopenia model.
Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Chung HJ, Blair NS, Millay DP, Morris AJ, Prideaux B, Finck BN, Quattrocelli M. Prabakaran AD, et al. Among authors: mcfarland k. J Clin Invest. 2024 May 3;134(11):e177427. doi: 10.1172/JCI177427. J Clin Invest. 2024. PMID: 38702076 Free PMC article.
Metabolic Pathophysiology of Cortical Spreading Depression: A Review.
Hill A, Amendolara AB, Small C, Guzman SC, Pfister D, McFarland K, Settelmayer M, Baker S, Donnelly S, Payne A, Sant D, Kriak J, Bills KB. Hill A, et al. Among authors: mcfarland k. Brain Sci. 2024 Oct 16;14(10):1026. doi: 10.3390/brainsci14101026. Brain Sci. 2024. PMID: 39452037 Free PMC article. Review.
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips J, Iturbe A, Erquizi A, Moore BD, Ryu D, Natu A, Dillon K, Torrellas J, Moran C, Ladd T, Afroz F, Islam T, Jagirdar J, Funk CC, Robinson M, Rangaraju S, Borchelt DR, Ertekin-Taner N, Kelly JW, Heppner FL, Johnson ECB, McFarland K, Levey AI, Prokop S, Seyfried NT, Golde TE. Levites Y, et al. Among authors: mcfarland k. Cell Rep Med. 2024 Aug 20;5(8):101669. doi: 10.1016/j.xcrm.2024.101669. Epub 2024 Aug 9. Cell Rep Med. 2024. PMID: 39127040 Free PMC article.
631 results