Shapiro RS - Search Results

1

Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost.

Bédard C, Gagnon-Arsenault I, Boisvert J, Plante S, Dubé AK, Pageau A, Fijarczyk A, Sharma J, Maroc L, Shapiro RS, Landry CR. Bédard C, et al. Among authors: shapiro rs. Nat Microbiol. 2024 Nov;9(11):3025-3040. doi: 10.1038/s41564-024-01819-2. Epub 2024 Oct 8. Nat Microbiol. 2024. PMID: 39379635

2

Mucin modulates microbial morphogenesis.

Sharma J, Shapiro RS. Sharma J, et al. Among authors: shapiro rs. Nat Chem Biol. 2022 Jul;18(7):684-686. doi: 10.1038/s41589-022-01053-z. Nat Chem Biol. 2022. PMID: 35668190 No abstract available.

3

Functional genetic characterization of stress tolerance and biofilm formation in Nakaseomyces (Candida) glabrata via a novel CRISPR activation system.

Maroc L, Shaker H, Shapiro RS. Maroc L, et al. Among authors: shapiro rs. mSphere. 2024 Feb 28;9(2):e0076123. doi: 10.1128/msphere.00761-23. Epub 2024 Jan 24. mSphere. 2024. PMID: 38265239 Free PMC article.

4

CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches.

Uthayakumar D, Sharma J, Wensing L, Shapiro RS. Uthayakumar D, et al. Among authors: shapiro rs. Front Genome Ed. 2021 Jan 8;2:606281. doi: 10.3389/fgeed.2020.606281. eCollection 2020. Front Genome Ed. 2021. PMID: 34713231 Free PMC article. Review.

5

A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans.

Wensing L, Sharma J, Uthayakumar D, Proteau Y, Chavez A, Shapiro RS. Wensing L, et al. Among authors: shapiro rs. mSphere. 2019 Feb 13;4(1):e00002-19. doi: 10.1128/mSphere.00002-19. mSphere. 2019. PMID: 30760609 Free PMC article.

6

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens.

Sharma J, Rosiana S, Razzaq I, Shapiro RS. Sharma J, et al. Among authors: shapiro rs. J Fungi (Basel). 2019 Feb 21;5(1):17. doi: 10.3390/jof5010017. J Fungi (Basel). 2019. PMID: 30795580 Free PMC article. Review.

7

The Canadian Fungal Research Network: current challenges and future opportunities.

Horianopoulos LC, Gluck-Thaler E, Benoit Gelber I, Cowen LE, Geddes-McAlister J, Landry CR, Schwartz IS, Scott JA, Sellam A, Sheppard DC, Spribille T, Subramaniam R, Walker AK, Harris SD, Shapiro RS, Gerstein AC. Horianopoulos LC, et al. Among authors: shapiro rs. Can J Microbiol. 2021 Jan;67(1):13-22. doi: 10.1139/cjm-2020-0263. Epub 2020 Jul 27. Can J Microbiol. 2021. PMID: 32717148 Free article.

8

High-content CRISPR screening.

Bock C, Datlinger P, Chardon F, Coelho MA, Dong MB, Lawson KA, Lu T, Maroc L, Norman TM, Song B, Stanley G, Chen S, Garnett M, Li W, Moffat J, Qi LS, Shapiro RS, Shendure J, Weissman JS, Zhuang X. Bock C, et al. Among authors: shapiro rs. Nat Rev Methods Primers. 2022;2(1):9. doi: 10.1038/s43586-022-00098-7. Epub 2022 Feb 10. Nat Rev Methods Primers. 2022. PMID: 37214176 Free PMC article.

9

Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans.

Gervais NC, La Bella AA, Wensing LF, Sharma J, Acquaviva V, Best M, Cadena López RO, Fogal M, Uthayakumar D, Chavez A, Santiago-Tirado F, Flores-Mireles AL, Shapiro RS. Gervais NC, et al. Among authors: shapiro rs. G3 (Bethesda). 2023 Feb 9;13(2):jkac301. doi: 10.1093/g3journal/jkac301. G3 (Bethesda). 2023. PMID: 36450451 Free PMC article.

10

Unearthing the story of the first antifungal drugs.

Shapiro RS. Shapiro RS. Nat Rev Microbiol. 2023 Oct;21(10):631. doi: 10.1038/s41579-023-00937-8. Nat Rev Microbiol. 2023. PMID: 37700051 No abstract available.

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