Zha S - Search Results

1

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Huang X, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Lin X, et al. Among authors: zha s. Mol Cell. 2024 Oct 17;84(20):3916-3931.e7. doi: 10.1016/j.molcel.2024.09.020. Epub 2024 Oct 8. Mol Cell. 2024. PMID: 39383878

2

ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.

Menolfi D, Zha S. Menolfi D, et al. Among authors: zha s. Cell Biosci. 2020 Jan 29;10:8. doi: 10.1186/s13578-020-0376-x. eCollection 2020. Cell Biosci. 2020. PMID: 32015826 Free PMC article. Review.

3

DNA-PKcs kinase activity orchestrates both end-processing and end-ligation.

Menolfi D, Zha S. Menolfi D, et al. Among authors: zha s. Trends Cell Biol. 2022 Feb;32(2):91-93. doi: 10.1016/j.tcb.2021.12.002. Epub 2021 Dec 22. Trends Cell Biol. 2022. PMID: 34953661

4

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites.

Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S. Lin X, et al. Among authors: zha s. Nucleic Acids Res. 2022 Apr 22;50(7):3958-3973. doi: 10.1093/nar/gkac188. Nucleic Acids Res. 2022. PMID: 35349716 Free PMC article.

5

Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging.

Zhang H, Lin X, Zha S. Zhang H, et al. Among authors: zha s. Biochem Soc Trans. 2022 Aug 31;50(4):1169-1177. doi: 10.1042/BST20220366. Biochem Soc Trans. 2022. PMID: 35959996

6

Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.

Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB. Schvartzman JM, et al. Among authors: zha s. Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12. Mol Cell. 2023. PMID: 37311462 Free PMC article.

7

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner.

Shao Z, Lee BJ, Zhang H, Lin X, Li C, Jiang W, Chirathivat N, Gershik S, Shen MM, Baer R, Zha S. Shao Z, et al. Among authors: zha s. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2301972120. doi: 10.1073/pnas.2301972120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487079 Free PMC article.

8

Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.

Jiang W, Crowe JL, Liu X, Nakajima S, Wang Y, Li C, Lee BJ, Dubois RL, Liu C, Yu X, Lan L, Zha S. Jiang W, et al. Among authors: zha s. Mol Cell. 2015 Apr 2;58(1):172-85. doi: 10.1016/j.molcel.2015.02.024. Epub 2015 Mar 26. Mol Cell. 2015. PMID: 25818648 Free PMC article.

9

The recent advances in non-homologous end-joining through the lens of lymphocyte development.

Wang XS, Lee BJ, Zha S. Wang XS, et al. Among authors: zha s. DNA Repair (Amst). 2020 Oct;94:102874. doi: 10.1016/j.dnarep.2020.102874. Epub 2020 Jun 25. DNA Repair (Amst). 2020. PMID: 32623318 Free PMC article. Review.

10

Targeting BRCA-mutated tumors in mitosis.

Menolfi D, Zha S. Menolfi D, et al. Among authors: zha s. Nat Cancer. 2021 Dec;2(12):1296-1297. doi: 10.1038/s43018-021-00293-7. Nat Cancer. 2021. PMID: 35121918 No abstract available.

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