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Page 1
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution.
Nguyen DD, Hooper WF, Liu W, Chu TR, Geiger H, Shelton JM, Shah M, Goldstein ZR, Winterkorn L, Helland A, Sigouros M, Manohar J, Moyer J, Al Assaad M, Semaan A, Cohen S, Madorsky Rowdo F, Wilkes D, Osman M, Singh RR, Sboner A, Valentine HL, Abbosh P, Tagawa ST, Nanus DM, Nauseef JT, Sternberg CN, Molina AM, Scherr D, Inghirami G, Mosquera JM, Elemento O, Robine N, Faltas BM. Nguyen DD, et al. Among authors: manohar j. Nature. 2024 Nov;635(8037):219-228. doi: 10.1038/s41586-024-07955-3. Epub 2024 Oct 9. Nature. 2024. PMID: 39385020 Free PMC article.
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Beg S, Bareja R, Ohara K, Eng KW, Wilkes DC, Pisapia DJ, Zoughbi WA, Kudman S, Zhang W, Rao R, Manohar J, Kane T, Sigouros M, Xiang JZ, Khani F, Robinson BD, Faltas BM, Sternberg CN, Sboner A, Beltran H, Elemento O, Mosquera JM. Beg S, et al. Among authors: manohar j. Transl Oncol. 2021 Jan;14(1):100944. doi: 10.1016/j.tranon.2020.100944. Epub 2020 Nov 12. Transl Oncol. 2021. PMID: 33190043 Free PMC article.
Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter.
Manohar J, Abedian S, Martini R, Kulm S, Salvatore M, Ho K, Christos P, Campion T, Imperato-McGinley J, Ibrahim S, Evering TH, Phillips E, Tamimi R, Bea V, Balogun OD, Sboner A, Elemento O, Davis MB. Manohar J, et al. medRxiv [Preprint]. 2021 Apr 7:2021.04.06.21254728. doi: 10.1101/2021.04.06.21254728. medRxiv. 2021. PMID: 33851193 Free PMC article. Preprint.
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
Al Zoughbi W, Fox J, Beg S, Papp E, Hissong E, Ohara K, Keefer L, Sigouros M, Kane T, Bockelman D, Nichol D, Patchell E, Bareja R, Karandikar A, Alnajar H, Cerqueira G, Guthrie VB, Verner E, Manohar J, Greco N, Wilkes D, Tagawa S, Malbari MS, Holcomb K, Eng KW, Shah M, Altorki NK, Sboner A, Nanus D, Faltas B, Sternberg CN, Simmons J, Houvras Y, Molina AM, Angiuoli S, Elemento O, Mosquera JM. Al Zoughbi W, et al. Among authors: manohar j. Oncologist. 2021 Nov;26(11):e1971-e1981. doi: 10.1002/onco.13905. Epub 2021 Aug 4. Oncologist. 2021. PMID: 34286887 Free PMC article.
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.
Shohdy KS, Bareja R, Sigouros M, Wilkes DC, Dorsaint P, Manohar J, Bockelman D, Xiang JZ, Kim R, Ohara K, Eng K, Mosquera JM, Elemento O, Sboner A, Alonso A, Faltas BM. Shohdy KS, et al. Among authors: manohar j. NPJ Genom Med. 2021 Aug 12;6(1):66. doi: 10.1038/s41525-021-00231-7. NPJ Genom Med. 2021. PMID: 34385467 Free PMC article.
Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Conteduca V, Ku SY, Fernandez L, Dago-Rodriquez A, Lee J, Jendrisak A, Slade M, Gilbertson C, Manohar J, Sigouros M, Wang Y, Dittamore R, Wenstrup R, Mosquera JM, Schonhoft JD, Beltran H. Conteduca V, et al. Among authors: manohar j. NPJ Precis Oncol. 2021 Aug 12;5(1):76. doi: 10.1038/s41698-021-00211-1. NPJ Precis Oncol. 2021. PMID: 34385567 Free PMC article.
Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Conteduca V, Ku SY, Fernandez L, Dago-Rodriquez A, Lee J, Jendrisak A, Slade M, Gilbertson C, Manohar J, Sigouros M, Wang Y, Dittamore R, Wenstrup R, Mosquera JM, Schonhoft JD, Beltran H. Conteduca V, et al. Among authors: manohar j. NPJ Precis Oncol. 2021 Sep 13;5(1):84. doi: 10.1038/s41698-021-00227-7. NPJ Precis Oncol. 2021. PMID: 34518634 Free PMC article. No abstract available.
Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.
Alnajar H, Ravichandran H, Figueiredo Rendeiro A, Ohara K, Al Zoughbi W, Manohar J, Greco N, Sigouros M, Fox J, Muth E, Angiuoli S, Faltas B, Shusterman M, Sternberg CN, Elemento O, Mosquera JM. Alnajar H, et al. Among authors: manohar j. Cold Spring Harb Mol Case Stud. 2022 Apr 28;8(3):a006151. doi: 10.1101/mcs.a006151. Print 2022 Apr. Cold Spring Harb Mol Case Stud. 2022. PMID: 35483877 Free PMC article.
Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment.
Sternberg CN, Shin N, Chernyshov K, Calabro F, Cerbone L, Procopio G, Miheecheva N, Sagaradze G, Zaichikova A, Samarina N, Boyko A, Brown JH, Yunusova L, Guevara D, Manohar J, Sigouros M, Al Assaad M, Elemento O, Mosquera JM. Sternberg CN, et al. Among authors: manohar j. Front Oncol. 2022 Oct 31;12:1006017. doi: 10.3389/fonc.2022.1006017. eCollection 2022. Front Oncol. 2022. PMID: 36387205 Free PMC article.
35 results