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Co-expression of μ and δ opioid receptors by mouse colonic nociceptors.
Guerrero-Alba R, Valdez-Morales EE, Jiménez-Vargas NN, Bron R, Poole D, Reed D, Castro J, Campaniello M, Hughes PA, Brierley SM, Bunnett N, Lomax AE, Vanner S. Guerrero-Alba R, et al. Br J Pharmacol. 2018 Jul;175(13):2622-2634. doi: 10.1111/bph.14222. Epub 2018 May 22. Br J Pharmacol. 2018. PMID: 29579315 Free PMC article.
Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.
Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ. Jiménez-Vargas NN, et al. Among authors: reed de. Gut. 2022 Apr;71(4):695-704. doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30. Gut. 2022. PMID: 33785555 Free PMC article.
Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity.
Baker CC, Sessenwein JL, Wood HM, Yu Y, Tsang Q, Alward TA, Jimenez Vargas NN, Omar AA, McDonnel A, Segal JP, Sjaarda CP, Bunnett NW, Schmidt BL, Caminero A, Boev N, Bannerman CA, Ghasemlou N, Sheth PM, Vanner SJ, Reed DE, Lomax AE. Baker CC, et al. Among authors: reed de. Cell Mol Gastroenterol Hepatol. 2024;18(4):101334. doi: 10.1016/j.jcmgh.2024.03.006. Epub 2024 Mar 16. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38494056 Free PMC article.
Emerging studies of human visceral nociceptors.
Reed DE, Vanner SJ. Reed DE, et al. Am J Physiol Gastrointest Liver Physiol. 2017 Mar 1;312(3):G201-G207. doi: 10.1152/ajpgi.00391.2016. Epub 2016 Dec 22. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28007748 Free article. Review.
156 results