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Page 1
HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status.
Leblond AL, Helmchen B, Ankavay M, Lenggenhager D, Jetzer J, Helmchen F, Yurtsever H, Parrotta R, Healy ME, Pöschel A, Markkanen E, Semmo N, Ferrié M, Cocquerel L, Seeger H, Hopfer H, Müllhaupt B, Gouttenoire J, Moradpour D, Gaspert A, Weber A. Leblond AL, et al. Among authors: ankavay m. Nat Commun. 2024 Oct 14;15(1):8849. doi: 10.1038/s41467-024-53072-0. Nat Commun. 2024. PMID: 39397005 Free PMC article.
The AP-1 adaptor complex is essential for intracellular trafficking of the ORF2 capsid protein and assembly of Hepatitis E virus.
Ferrié M, Alexandre V, Montpellier C, Bouquet P, Tubiana T, Mézière L, Ankavay M, Bentaleb C, Dubuisson J, Bressanelli S, Aliouat-Denis CM, Rouillé Y, Cocquerel L. Ferrié M, et al. Among authors: ankavay m. Cell Mol Life Sci. 2024 Aug 9;81(1):335. doi: 10.1007/s00018-024-05367-0. Cell Mol Life Sci. 2024. PMID: 39117755 Free PMC article.
The endocytic recycling compartment serves as a viral factory for hepatitis E virus.
Bentaleb C, Hervouet K, Montpellier C, Camuzet C, Ferrié M, Burlaud-Gaillard J, Bressanelli S, Metzger K, Werkmeister E, Ankavay M, Janampa NL, Marlet J, Roux J, Deffaud C, Goffard A, Rouillé Y, Dubuisson J, Roingeard P, Aliouat-Denis CM, Cocquerel L. Bentaleb C, et al. Among authors: ankavay m. Cell Mol Life Sci. 2022 Dec 3;79(12):615. doi: 10.1007/s00018-022-04646-y. Cell Mol Life Sci. 2022. PMID: 36460928 Free PMC article.
An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell.
Hervouet K, Ferrié M, Ankavay M, Montpellier C, Camuzet C, Alexandre V, Dembélé A, Lecoeur C, Foe AT, Bouquet P, Hot D, Vausselin T, Saliou JM, Salomé-Desnoulez S, Vandeputte A, Marsollier L, Brodin P, Dreux M, Rouillé Y, Dubuisson J, Aliouat-Denis CM, Cocquerel L. Hervouet K, et al. Among authors: ankavay m. PLoS Pathog. 2022 Aug 25;18(8):e1010798. doi: 10.1371/journal.ppat.1010798. eCollection 2022 Aug. PLoS Pathog. 2022. PMID: 36007070 Free PMC article.
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.
Crouchet E, Bandiera S, Fujiwara N, Li S, El Saghire H, Fernández-Vaquero M, Riedl T, Sun X, Hirschfield H, Jühling F, Zhu S, Roehlen N, Ponsolles C, Heydmann L, Saviano A, Qian T, Venkatesh A, Lupberger J, Verrier ER, Sojoodi M, Oudot MA, Duong FHT, Masia R, Wei L, Thumann C, Durand SC, González-Motos V, Heide D, Hetzer J, Nakagawa S, Ono A, Song WM, Higashi T, Sanchez R, Kim RS, Bian CB, Kiani K, Croonenborghs T, Subramanian A, Chung RT, Straub BK, Schuppan D, Ankavay M, Cocquerel L, Schaeffer E, Goossens N, Koh AP, Mahajan M, Nair VD, Gunasekaran G, Schwartz ME, Bardeesy N, Shalek AK, Rozenblatt-Rosen O, Regev A, Felli E, Pessaux P, Tanabe KK, Heikenwälder M, Schuster C, Pochet N, Zeisel MB, Fuchs BC, Hoshida Y, Baumert TF. Crouchet E, et al. Among authors: ankavay m. Nat Commun. 2021 Sep 17;12(1):5525. doi: 10.1038/s41467-021-25468-9. Nat Commun. 2021. PMID: 34535664 Free PMC article.
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