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Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma.
Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, Okada R, Reilly K, Widemann B, Pommier Y, Elloumi F, Dhall A, Patel M, Aber E, Contreras-Burrola C, Kaplan R, Martinez D, Pogoriler J, Hamilton AK, Diskin SJ, Maris JM, Robey RW, Gottesman MM, Rivero JD, Roper N. Sun NY, et al. Among authors: robey rw. bioRxiv [Preprint]. 2024 Oct 11:2024.10.09.617077. doi: 10.1101/2024.10.09.617077. bioRxiv. 2024. PMID: 39416174 Free PMC article. Preprint.
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier.
Thomas JR, Frye WJE, Robey RW, Warner AC, Butcher D, Matta JL, Morgan TC, Edmondson EF, Salazar PB, Ambudkar SV, Gottesman MM. Thomas JR, et al. Among authors: robey rw. bioRxiv [Preprint]. 2024 Jan 8:2023.05.18.539313. doi: 10.1101/2023.05.18.539313. bioRxiv. 2024. Update in: Fluids Barriers CNS. 2024 Mar 15;21(1):27. doi: 10.1186/s12987-024-00529-5 PMID: 37425689 Free PMC article. Updated. Preprint.
Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib.
Pang Y, Li Q, Sergi Z, Yu G, Sang X, Kim O, Wang H, Ranjan A, Merchant M, Oudit B, Robey RW, Soheilian F, Tran B, Núñez FJ, Zhang M, Song H, Zhang W, Davis D, Gilbert MR, Gottesman MM, Liu Z, Khan J, Thomas CJ, Castro MG, Gujral TS, Wu J. Pang Y, et al. Among authors: robey rw. bioRxiv [Preprint]. 2024 Jan 2:2023.06.29.547143. doi: 10.1101/2023.06.29.547143. bioRxiv. 2024. PMID: 37786680 Free PMC article. Preprint.
The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species.
González Dalmasy JM, Fitzsimmons CM, Frye WJE, Perciaccante AJ, Jewell CP, Jenkins LM, Batista PJ, Robey RW, Gottesman MM. González Dalmasy JM, et al. Among authors: robey rw. Chem Biol Interact. 2024 May 1;394:110989. doi: 10.1016/j.cbi.2024.110989. Epub 2024 Apr 3. Chem Biol Interact. 2024. PMID: 38574836
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.
Lim S, Kwak M, Kang J, Cesaire M, Tang K, Robey RW, Frye WJE, Karim B, Butcher D, Lizak MJ, Dalmage M, Foster B, Nuechterlein N, Eberhart C, Cimino PJ, Gottesman MM, Jackson S. Lim S, et al. Among authors: robey rw. Acta Neuropathol Commun. 2024 Apr 8;12(1):56. doi: 10.1186/s40478-024-01763-6. Acta Neuropathol Commun. 2024. PMID: 38589905 Free PMC article.
Carrier-Free, Amorphous Verteporfin Nanodrug for Enhanced Photodynamic Cancer Therapy and Brain Drug Delivery.
Quinlan JA, Inglut CT, Srivastava P, Rahman I, Stabile J, Gaitan B, Arnau Del Valle C, Baumiller K, Gaur A, Chiou WA, Karim B, Connolly N, Robey RW, Woodworth GF, Gottesman MM, Huang HC. Quinlan JA, et al. Among authors: robey rw. Adv Sci (Weinh). 2024 May;11(17):e2302872. doi: 10.1002/advs.202302872. Epub 2024 Mar 6. Adv Sci (Weinh). 2024. PMID: 38445882 Free PMC article.
A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples.
Arakawa Y, Elloumi F, Varma S, Khandagale P, Jo U, Kumar S, Roper N, Reinhold WC, Robey RW, Takebe N, Gottesman MM, Thomas CJ, Boeva V, Berruti A, Abate A, Tamburello M, Sigala S, Hantel C, Weigand I, Wierman ME, Kiseljak-Vassiliades K, Del Rivero J, Pommier Y. Arakawa Y, et al. Among authors: robey rw. Cancer Res Commun. 2024 Sep 1;4(9):2384-2398. doi: 10.1158/2767-9764.CRC-24-0100. Cancer Res Commun. 2024. PMID: 39162009 Free PMC article.
123 results