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138 results

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Visualization of membrane localization and the functional state of CB2R pools using matched agonist and inverse agonist probe pairs.
Wąsińska-Kałwa M, Omran A, Mach L, Scipioni L, Bouma J, Li X, Radetzki S, Mostinski Y, Schippers M, Gazzi T, van der Horst C, Brennecke B, Hanske A, Kolomeets Y, Guba W, Sykes D, von Kries JP, Broichhagen J, Hua T, Veprintsev D, Heitman LH, Oddi S, Maccarrone M, Grether U, Nazare M. Wąsińska-Kałwa M, et al. Among authors: mach l. Chem Sci. 2024 Oct 3;15(44):18443-54. doi: 10.1039/d4sc00402g. Online ahead of print. Chem Sci. 2024. PMID: 39430942 Free PMC article.
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.
Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M. Gazzi T, et al. Among authors: mach l. Chem Sci. 2022 Apr 1;13(19):5539-5545. doi: 10.1039/d1sc06659e. eCollection 2022 May 18. Chem Sci. 2022. PMID: 35694350 Free PMC article.
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R).
Mach L, Omran A, Bouma J, Radetzki S, Sykes DA, Guba W, Li X, Höffelmeyer C, Hentsch A, Gazzi T, Mostinski Y, Wasinska-Kalwa M, de Molnier F, van der Horst C, von Kries JP, Vendrell M, Hua T, Veprintsev DB, Heitman LH, Grether U, Nazare M. Mach L, et al. J Med Chem. 2024 Jul 25;67(14):11841-11867. doi: 10.1021/acs.jmedchem.4c00465. Epub 2024 Jul 11. J Med Chem. 2024. PMID: 38990855 Free PMC article.
An organotypic atlas of human vascular cells.
Barnett SN, Cujba AM, Yang L, Maceiras AR, Li S, Kedlian V, Pett JP, Polanski K, Miranda AMA, Xu C, Cranley J, Kanemaru K, Lee M, Mach L, Perera S, Tudor C, Joseph PD, Pritchard S, Toscano-Rivalta R, Tuong K, Bolt L, Petryszak R, Prete M, Cakir B, Huseynov A, Sarropoulos I, Chowdhury RA, Elmentaite R, Madissoon E, Oliver A, Campos L, Brazovskaja A, Gomes T, Treutlein B, Kim CN, Nowakowski TJ, Meyer KB, Randi AM, Noseda M, Teichmann SA. Barnett SN, et al. Among authors: mach l. Nat Med. 2024 Nov 20. doi: 10.1038/s41591-024-03376-x. Online ahead of print. Nat Med. 2024. PMID: 39566559
Arrhythmic Risk Stratification by Cardiovascular Magnetic Resonance Imaging in Patients With Nonischemic Cardiomyopathy.
Hammersley DJ, Zegard A, Androulakis E, Jones RE, Okafor O, Hatipoglu S, Mach L, Lota AS, Khalique Z, de Marvao A, Gulati A, Baruah R, Guha K, Ware JS, Tayal U, Pennell DJ, Halliday BP, Qiu T, Prasad SK, Leyva F. Hammersley DJ, et al. Among authors: mach l. J Am Coll Cardiol. 2024 Oct 8;84(15):1407-1420. doi: 10.1016/j.jacc.2024.06.046. Epub 2024 Aug 30. J Am Coll Cardiol. 2024. PMID: 39217566 Free PMC article.
Precision prediction of heart failure events in patients with dilated cardiomyopathy and mildly reduced ejection fraction using multi-parametric cardiovascular magnetic resonance.
Hammersley DJ, Mukhopadhyay S, Chen X, Jones RE, Ragavan A, Javed S, Rajabali H, Androulakis E, Curran L, Mach L, Khalique Z, Baruah R, Guha K, Gregson J, Zhao S, De Marvao A, Tayal U, Lota AS, Ware JS, Pennell DJ, Prasad SK, Halliday BP. Hammersley DJ, et al. Among authors: mach l. Eur J Heart Fail. 2024 Aug 15:10.1002/ejhf.3425. doi: 10.1002/ejhf.3425. Online ahead of print. Eur J Heart Fail. 2024. PMID: 39143936 Free PMC article.
Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy.
Nicastro M, Vermeer AMC, Postema PG, Tadros R, Bowling FZ, Aegisdottir HM, Tragante V, Mach L, Postma AV, Lodder EM, van Duijvenboden K, Zwart R, Beekman L, Wu L, van der Zwaag PA, Alders M, Allouba M, Aguib Y, Santomel JL, de Una D, Monserrat L, Miranda AMA, Kanemaru K, Cranley J, van Zeggeren IE, Aronica EMA, Ripolone M, Zanotti S, Sveinbjornsson G, Ivarsdottir EV, Hólm H, Guðbjartsson DF, Skúladóttir ÁT, Stefánsson K, Nadauld L, Knowlton KU, Ostrowski SR, Sørensen E, Vesterager Pedersen OB, Ghouse J, Rand S, Bundgaard H, Ullum H, Erikstrup C, Aagaard B, Bruun MT, Christiansen M, Jensen HK, Carere DA, Cummings CT, Fishler K, Tøring PM, Brusgaard K, Juul TM, Saaby L, Winkel BG, Mogensen J, Fortunato F, Comi GP, Ronchi D, van Tintelen JP, Noseda M, Airola MV, Christiaans I, Wilde AAM, Wilders R, Clur SA, Verkerk AO, Bezzina CR, Lahrouchi N. Nicastro M, et al. Among authors: mach l. medRxiv [Preprint]. 2024 Jul 5:2024.07.04.24309755. doi: 10.1101/2024.07.04.24309755. medRxiv. 2024. PMID: 39006410 Free PMC article. Preprint.
Comparative prognostic importance of measures of left atrial structure and function in non-ischaemic dilated cardiomyopathy.
Hammersley DJ, Mukhopadhyay S, Chen X, Cheng L, Jones RE, Mach L, Curran L, Yazdani M, Iacob A, Lota AS, Khalique Z, De Marvao A, Baruah R, Guha K, Ware JS, Gregson J, Zhao S, Pennell DJ, Tayal U, Prasad SK, Halliday BP. Hammersley DJ, et al. Among authors: mach l. Eur Heart J Cardiovasc Imaging. 2024 Oct 30;25(11):1566-1574. doi: 10.1093/ehjci/jeae080. Eur Heart J Cardiovasc Imaging. 2024. PMID: 38492215 Free PMC article.
138 results