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Visualization of membrane localization and the functional state of CB2R pools using matched agonist and inverse agonist probe pairs.
Wąsińska-Kałwa M, Omran A, Mach L, Scipioni L, Bouma J, Li X, Radetzki S, Mostinski Y, Schippers M, Gazzi T, van der Horst C, Brennecke B, Hanske A, Kolomeets Y, Guba W, Sykes D, von Kries JP, Broichhagen J, Hua T, Veprintsev D, Heitman LH, Oddi S, Maccarrone M, Grether U, Nazare M. Wąsińska-Kałwa M, et al. Among authors: von kries jp. Chem Sci. 2024 Oct 3;15(44):18443-54. doi: 10.1039/d4sc00402g. Online ahead of print. Chem Sci. 2024. PMID: 39430942 Free PMC article.
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R).
Mach L, Omran A, Bouma J, Radetzki S, Sykes DA, Guba W, Li X, Höffelmeyer C, Hentsch A, Gazzi T, Mostinski Y, Wasinska-Kalwa M, de Molnier F, van der Horst C, von Kries JP, Vendrell M, Hua T, Veprintsev DB, Heitman LH, Grether U, Nazare M. Mach L, et al. Among authors: von kries jp. J Med Chem. 2024 Jul 25;67(14):11841-11867. doi: 10.1021/acs.jmedchem.4c00465. Epub 2024 Jul 11. J Med Chem. 2024. PMID: 38990855 Free PMC article.
Human cerebrospinal fluid monoclonal CASPR2 autoantibodies induce changes in electrophysiology, functional MRI, and behavior in rodent models.
van Hoof S, Kreye J, Cordero-Gómez C, Hoffmann J, Momsen Reincke S, Sánchez-Sendin E, Duong SL, Upadhya M, Dhangar D, Michór P, Woodhall GL, Küpper M, Oder A, Kuchling J, Koch SP, Mueller S, Boehm-Sturm P, von Kries JP, Finke C, Kirschstein T, Wright SK, Prüss H. van Hoof S, et al. Among authors: von kries jp. Brain Behav Immun. 2024 Nov;122:266-278. doi: 10.1016/j.bbi.2024.08.027. Epub 2024 Aug 13. Brain Behav Immun. 2024. PMID: 39142424 Free article.
Identification of Human TRIAC Transmembrane Transporters.
Becker PC, Güth-Steffens M, Lazarow K, Sonntag N, Braun D, Masfaka I, Renko K, Schomburg L, Köhrle J, von Kries JP, Schweizer U, Krause G, Protze J. Becker PC, et al. Among authors: von kries jp. Thyroid. 2024 Jul;34(7):920-930. doi: 10.1089/thy.2023.0592. Epub 2024 Jul 1. Thyroid. 2024. PMID: 38801167
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors.
Specker E, Wesolowski R, Schütz A, Matthes S, Mallow K, Wasinska-Kalwa M, Winkler L, Oder A, Alenina N, Pleimes D, von Kries JP, Heinemann U, Bader M, Nazaré M. Specker E, et al. Among authors: von kries jp. J Med Chem. 2023 Nov 9;66(21):14866-14896. doi: 10.1021/acs.jmedchem.3c01454. Epub 2023 Oct 31. J Med Chem. 2023. PMID: 37905925
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan S, Schöpe PC, Lewis J, Putzker K, Uhrig U, Specker E, von Kries JP, Lindemann P, Omran A, Sanchez-Ibarra HE, Unger A, Zischinsky ML, Klebl B, Walther W, Nazaré M, Kobelt D, Stein U. Yan S, et al. Among authors: von kries jp. Biomed Pharmacother. 2023 Dec;168:115698. doi: 10.1016/j.biopha.2023.115698. Epub 2023 Oct 21. Biomed Pharmacother. 2023. PMID: 37865992 Free article.
83 results