Hwang H - Search Results

1

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.

Kim HJ, Kim H, Song J, Hong JY, Lee EH, Londhe AM, Choi JW, Park SJ, Oh E, Yoon H, Hwang H, Hahn D, Jung K, Kwon S, Kadayat TM, Ma MJ, Joo J, Kim J, Bae JH, Hwang H, Pae AN, Cho SJ, Park JH, Chin J, Kang H, Park KD. Kim HJ, et al. Among authors: hwang h. Theranostics. 2024 Sep 16;14(16):6088-6108. doi: 10.7150/thno.96707. eCollection 2024. Theranostics. 2024. PMID: 39431021 Free PMC article.

2

Synthesis and evaluation of an orally available "Y"-shaped biaryl peroxisome proliferator-activated receptor δ agonist.

Kim DS, Lee J, Londhe AM, Kadayat TM, Joo J, Hwang H, Kim KH, Pae AN, Chin J, Cho SJ, Kang H. Kim DS, et al. Among authors: hwang h. Bioorg Med Chem. 2018 Aug 15;26(15):4382-4389. doi: 10.1016/j.bmc.2018.06.044. Epub 2018 Jul 20. Bioorg Med Chem. 2018. PMID: 30054191

3

Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.

Lim JW, Kim SK, Choi SY, Kim DH, Gadhe CG, Lee HN, Kim HJ, Kim J, Cho SJ, Hwang H, Seong J, Jeong KS, Lee JY, Lim SM, Lee JW, Pae AN. Lim JW, et al. Among authors: hwang h. Eur J Med Chem. 2018 Sep 5;157:405-422. doi: 10.1016/j.ejmech.2018.07.071. Epub 2018 Aug 3. Eur J Med Chem. 2018. PMID: 30103190

4

Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model.

Kim S, Indu Viswanath AN, Park JH, Lee HE, Park AY, Choi JW, Kim HJ, Londhe AM, Jang BK, Lee J, Hwang H, Lim SM, Pae AN, Park KD. Kim S, et al. Among authors: hwang h. Neuropharmacology. 2020 May 1;167:107989. doi: 10.1016/j.neuropharm.2020.107989. Epub 2020 Feb 5. Neuropharmacology. 2020. PMID: 32032607

5

The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents.

Kim T, Morshed MN, Londhe AM, Lim JW, Lee HE, Cho S, Cho SJ, Hwang H, Lim SM, Lee JY, Lee J, Pae AN. Kim T, et al. Among authors: hwang h. J Enzyme Inhib Med Chem. 2021 Dec;36(1):831-846. doi: 10.1080/14756366.2021.1900158. J Enzyme Inhib Med Chem. 2021. PMID: 33752569 Free PMC article.

6

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Park SJ, Yeon SK, Kim Y, Kim HJ, Kim S, Kim J, Choi JW, Kim B, Lee EH, Kim R, Seo SH, Lee J, Kim JW, Lee HY, Hwang H, Bahn YS, Cheong E, Park JH, Park KD. Park SJ, et al. Among authors: hwang h. J Med Chem. 2022 Feb 24;65(4):3539-3562. doi: 10.1021/acs.jmedchem.1c01979. Epub 2022 Jan 25. J Med Chem. 2022. PMID: 35077170

7

Discovery of the therapeutic potential of PPARδ agonist bearing 1,3,4- thiadiazole in inflammatory disorders.

Kim J, Kadayat TM, Lee JE, Kwon S, Jung K, Hwang JS, Kwon OB, Kim YJ, Choi YK, Park KG, Hwang H, Cho SJ, Lee T, Jeon YH, Chin J. Kim J, et al. Among authors: hwang h, hwang js. Eur J Med Chem. 2024 Dec 5;279:116856. doi: 10.1016/j.ejmech.2024.116856. Epub 2024 Sep 12. Eur J Med Chem. 2024. PMID: 39270454

8

Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica.

Ju EJ, Yeon SK, Park JH, Cheon SY, Choi JW, Ha T, Jang BK, Kim S, Kang YG, Hwang H, Cho SJ, Cheong E, Bahn YS, Pae AN, Kim SM, Park KD. Ju EJ, et al. Among authors: hwang h. ChemMedChem. 2016 Feb 17;11(4):377-81. doi: 10.1002/cmdc.201500546. Epub 2016 Jan 25. ChemMedChem. 2016. PMID: 26804736

9

Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.

Kim J, Song J, Ji HD, Yoo EK, Lee JE, Lee SB, Oh JM, Lee S, Hwang JS, Yoon H, Kim DS, Lee SJ, Jeong M, Lee S, Kim KH, Choi HS, Lee SW, Park KG, Lee IK, Kim SH, Hwang H, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: hwang h, hwang js. J Med Chem. 2019 Feb 28;62(4):1837-1858. doi: 10.1021/acs.jmedchem.8b01296. Epub 2019 Feb 4. J Med Chem. 2019. PMID: 30657313

10

A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.

Singh TD, Song J, Kim J, Chin J, Ji HD, Lee JE, Lee SB, Yoon H, Yu JH, Kim SK, Yoon GS, Hwang H, Lee HW, Oh JM, Lee SW, Lee J, Choi HS, Na SY, Choi WI, Park YJ, Song YS, Kim YA, Lee IK, Cho SJ, Jeon YH. Singh TD, et al. Among authors: hwang h. Clin Cancer Res. 2019 Aug 15;25(16):5069-5081. doi: 10.1158/1078-0432.CCR-18-3007. Epub 2019 Apr 22. Clin Cancer Res. 2019. PMID: 31010838

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