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Page 1
Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E. Myers JW, et al. Among authors: coate kc. bioRxiv [Preprint]. 2024 Nov 1:2024.10.28.620705. doi: 10.1101/2024.10.28.620705. bioRxiv. 2024. PMID: 39553975 Free PMC article. Preprint.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Mol Metab. 2024 Oct 20;90:102050. doi: 10.1016/j.molmet.2024.102050. Online ahead of print. Mol Metab. 2024. PMID: 39433176 Free PMC article.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606926. doi: 10.1101/2024.08.06.606926. bioRxiv. 2024. Update in: Mol Metab. 2024 Oct 20;90:102050. doi: 10.1016/j.molmet.2024.102050 PMID: 39149351 Free PMC article. Updated. Preprint.
Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.
Coate KC, Ramnanan CJ, Smith M, Winnick JJ, Kraft G, Irimia JM, Farmer B, Donahue P, Roach PJ, Cherrington AD, Edgerton DS. Coate KC, et al. bioRxiv [Preprint]. 2023 Oct 1:2023.09.28.559999. doi: 10.1101/2023.09.28.559999. bioRxiv. 2023. Update in: Am J Physiol Endocrinol Metab. 2024 Apr 1;326(4):E428-E442. doi: 10.1152/ajpendo.00316.2023 PMID: 37808670 Free PMC article. Updated. Preprint.
Defining unique structural features in the MAFA and MAFB transcription factors that control Insulin gene activity.
Cha J, Tong X, Coate KC, Guo M, Liu JH, Reynolds G, Walker EM, Stein RA, Mchaourab H, Stein R. Cha J, et al. Among authors: coate kc. bioRxiv [Preprint]. 2024 May 29:2023.08.23.554429. doi: 10.1101/2023.08.23.554429. bioRxiv. 2024. Update in: J Biol Chem. 2024 Oct 28;300(12):107938. doi: 10.1016/j.jbc.2024.107938 PMID: 37662349 Free PMC article. Updated. Preprint.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. Among authors: coate kc. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
38 results