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Page 1
The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo.
Echterhof A, Dharmaraj T, Khosravi A, McBride R, Miesel L, Chia JH, Blankenberg PM, Lin KY, Shen CC, Lee YL, Yeh YC, Liao WT, Blankenberg FG, Dąbrowska K, Amanatullah DF, Frymoyer AR, Bollyky PL. Echterhof A, et al. Among authors: miesel l. JCI Insight. 2024 Oct 22;9(20):e181309. doi: 10.1172/jci.insight.181309. JCI Insight. 2024. PMID: 39435664 Free PMC article.
The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo.
Echterhof A, Dharmaraj T, McBride R, Berry J, Hopkins M, Selvakumar H, Miesel L, Chia JH, Lin KY, Shen CC, Lee YL, Yeh YC, Liao WT, Suh G, Blankenberg FG, Frymoyer AR, Bollyky PL. Echterhof A, et al. Among authors: miesel l. bioRxiv [Preprint]. 2024 Jan 27:2024.01.25.577154. doi: 10.1101/2024.01.25.577154. bioRxiv. 2024. Update in: JCI Insight. 2024 Oct 22;9(20):e181309. doi: 10.1172/jci.insight.181309 PMID: 38328123 Free PMC article. Updated. Preprint.
Structure activity relationship of N-1 substituted 1,5-naphthyrid-2-one analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-9).
Singh SB, Tan CM, Kaelin D, Meinke PT, Miesel L, Olsen DB, Fukuda H, Kishii R, Takei M, Ohata K, Takeuchi T, Shibue T, Takano H, Nishimura A, Fukuda Y. Singh SB, et al. Among authors: miesel l. Bioorg Med Chem Lett. 2022 Nov 1;75:128808. doi: 10.1016/j.bmcl.2022.128808. Epub 2022 May 21. Bioorg Med Chem Lett. 2022. PMID: 35609741 Clinical Trial.
FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development.
Byrne JM, Waack U, Weinstein EA, Joshi A, Shurland SM, Iarikov D, Bulitta JB, Diep BA, Guina T, Hope WW, Lawrenz MB, Lepak AJ, Luna BM, Miesel L, Phipps AJ, Walsh TJ, Weiss W, Amini T, Farley JJ. Byrne JM, et al. Among authors: miesel l. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01983-20. doi: 10.1128/AAC.01983-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33106262 Free PMC article. Review.
Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa.
Krause KM, Haglund CM, Hebner C, Serio AW, Lee G, Nieto V, Cohen F, Kane TR, Machajewski TD, Hildebrandt D, Pillar C, Thwaites M, Hall D, Miesel L, Hackel M, Burek A, Andrews LD, Armstrong E, Swem L, Jubb A, Cirz RT. Krause KM, et al. Among authors: miesel l. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00977-19. doi: 10.1128/AAC.00977-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451507 Free PMC article.
Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters.
Lakota EA, Bader JC, Ong V, Bartizal K, Miesel L, Andes DR, Bhavnani SM, Rubino CM, Ambrose PG, Lepak AJ. Lakota EA, et al. Among authors: miesel l. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e00758-17. doi: 10.1128/AAC.00758-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28848022 Free PMC article.
In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase.
Tan CM, Gill CJ, Wu J, Toussaint N, Yin J, Tsuchiya T, Garlisi CG, Kaelin D, Meinke PT, Miesel L, Olsen DB, Lagrutta A, Fukuda H, Kishii R, Takei M, Oohata K, Takeuchi T, Shibue T, Takano H, Nishimura A, Fukuda Y, Singh SB. Tan CM, et al. Among authors: miesel l. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4830-9. doi: 10.1128/AAC.00619-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27246784 Free PMC article.
32 results