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Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.
Oleaga C, Bernabini C, Smith AS, Srinivasan B, Jackson M, McLamb W, Platt V, Bridges R, Cai Y, Santhanam N, Berry B, Najjar S, Akanda N, Guo X, Martin C, Ekman G, Esch MB, Langer J, Ouedraogo G, Cotovio J, Breton L, Shuler ML, Hickman JJ. Oleaga C, et al. Among authors: jackson m. Sci Rep. 2016 Feb 3;6:20030. doi: 10.1038/srep20030. Sci Rep. 2016. PMID: 26837601 Free PMC article.
Validation of a functional human AD model with four AD therapeutics utilizing patterned iPSC-derived cortical neurons integrated with microelectrode arrays.
Caneus J, Autar K, Akanda N, Grillo M, Long C, Jackson M, Lindquist S, Guo X, Morgan D, Hickman JJ. Caneus J, et al. Among authors: jackson m. Res Sq [Preprint]. 2024 May 20:rs.3.rs-4313679. doi: 10.21203/rs.3.rs-4313679/v1. Res Sq. 2024. Update in: Sci Rep. 2024 Oct 22;14(1):24875. doi: 10.1038/s41598-024-73869-9 PMID: 38826367 Free PMC article. Updated. Preprint.
A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ42 and tau-induced pathophysiological effects on long-term potentiation.
Caneus J, Akanda N, Rumsey JW, Guo X, Jackson M, Long CJ, Sommerhage F, Georgieva S, Kanaan NM, Morgan D, Hickman JJ. Caneus J, et al. Among authors: jackson m. Alzheimers Dement (N Y). 2020 May 27;6(1):e12029. doi: 10.1002/trc2.12029. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 32490141 Free PMC article.
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.
Oleaga C, Riu A, Rothemund S, Lavado A, McAleer CW, Long CJ, Persaud K, Narasimhan NS, Tran M, Roles J, Carmona-Moran CA, Sasserath T, Elbrecht DH, Kumanchik L, Bridges LR, Martin C, Schnepper MT, Ekman G, Jackson M, Wang YI, Note R, Langer J, Teissier S, Hickman JJ. Oleaga C, et al. Among authors: jackson m. Biomaterials. 2018 Nov;182:176-190. doi: 10.1016/j.biomaterials.2018.07.062. Epub 2018 Aug 4. Biomaterials. 2018. PMID: 30130706 Free PMC article.
A Human-Based Functional NMJ System for Personalized ALS Modeling and Drug Testing.
Guo X, Smith V, Jackson M, Tran M, Thomas M, Patel A, Lorusso E, Nimbalkar S, Cai Y, McAleer CW, Wang Y, Long CJ, Hickman JJ. Guo X, et al. Among authors: jackson m. Adv Ther (Weinh). 2020 Nov;3(11):2000133. doi: 10.1002/adtp.202000133. Epub 2020 Aug 11. Adv Ther (Weinh). 2020. PMID: 33709015 Free PMC article.
Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies.
Rumsey JW, Lorance C, Jackson M, Sasserath T, McAleer CW, Long CJ, Goswami A, Russo MA, Raja SM, Gable KL, Emmett D, Hobson-Webb LD, Chopra M, Howard JF Jr, Guptill JT, Storek MJ, Alonso-Alonso M, Atassi N, Panicker S, Parry G, Hammond T, Hickman JJ. Rumsey JW, et al. Among authors: jackson m. Adv Ther (Weinh). 2022 Jun;5(6):2200030. doi: 10.1002/adtp.202200030. Epub 2022 Apr 5. Adv Ther (Weinh). 2022. PMID: 36211621 Free PMC article.
5,142 results