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Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy.
Keshari S, Shavkunov AS, Miao Q, Saha A, Minowa T, Molgora M, Williams CD, Chaib M, Highsmith AM, Pineda JE, Alekseev S, Alspach E, Hu KH, Colonna M, Pauken KE, Chen K, Gubin MM. Keshari S, et al. Among authors: molgora m. Cell Rep. 2024 Nov 26;43(11):114875. doi: 10.1016/j.celrep.2024.114875. Epub 2024 Oct 23. Cell Rep. 2024. PMID: 39446585 Free article.
TREM2: A new player in the tumor microenvironment.
Molgora M, Liu YA, Colonna M, Cella M. Molgora M, et al. Semin Immunol. 2023 May;67:101739. doi: 10.1016/j.smim.2023.101739. Epub 2023 Mar 28. Semin Immunol. 2023. PMID: 36989543 Review.
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.
Park MD, Reyes-Torres I, LeBerichel J, Hamon P, LaMarche NM, Hegde S, Belabed M, Troncoso L, Grout JA, Magen A, Humblin E, Nair A, Molgora M, Hou J, Newman JH, Farkas AM, Leader AM, Dawson T, D'Souza D, Hamel S, Sanchez-Paulete AR, Maier B, Bhardwaj N, Martin JC, Kamphorst AO, Kenigsberg E, Casanova-Acebes M, Horowitz A, Brown BD, De Andrade LF, Colonna M, Marron TU, Merad M. Park MD, et al. Among authors: molgora m. Nat Immunol. 2023 May;24(5):792-801. doi: 10.1038/s41590-023-01475-4. Epub 2023 Apr 20. Nat Immunol. 2023. PMID: 37081148 Free PMC article.
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Brioschi S, Belk JA, Peng V, Molgora M, Rodrigues PF, Nguyen KM, Wang S, Du S, Wang WL, Grajales-Reyes GE, Ponce JM, Yuede CM, Li Q, Baer JM, DeNardo DG, Gilfillan S, Cella M, Satpathy AT, Colonna M. Brioschi S, et al. Among authors: molgora m. Immunity. 2023 May 9;56(5):1027-1045.e8. doi: 10.1016/j.immuni.2023.01.028. Epub 2023 Feb 14. Immunity. 2023. PMID: 36791722 Free PMC article.
Amplification of autoimmune organ damage by NKp46-activated ILC1s.
Biniaris-Georgallis SI, Aschman T, Stergioula K, Schreiber F, Jafari V, Taranko A, Karmalkar T, Kasapi A, Lenac Rovis T, Jelencic V, Bejarano DA, Fabry L, Papacharalampous M, Mattiola I, Molgora M, Hou J, Hublitz KW, Heinrich F, Guerra GM, Durek P, Patone G, Lindberg EL, Maatz H, Hölsken O, Krönke G, Mortha A, Voll RE, Clarke AJ, Hauser AE, Colonna M, Thurley K, Schlitzer A, Schneider C, Stamatiades EG, Mashreghi MF, Jonjic S, Hübner N, Diefenbach A, Kanda M, Triantafyllopoulou A. Biniaris-Georgallis SI, et al. Among authors: molgora m. Nature. 2024 Oct;634(8035):952-960. doi: 10.1038/s41586-024-07907-x. Epub 2024 Aug 13. Nature. 2024. PMID: 39137897
TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M. Di Luccia B, et al. Among authors: molgora m. Sci Immunol. 2024 May 17;9(95):eadi5374. doi: 10.1126/sciimmunol.adi5374. Epub 2024 May 17. Sci Immunol. 2024. PMID: 38758808 Free PMC article.
Lipid-Associated Macrophages Are Induced by Cancer-Associated Fibroblasts and Mediate Immune Suppression in Breast Cancer.
Timperi E, Gueguen P, Molgora M, Magagna I, Kieffer Y, Lopez-Lastra S, Sirven P, Baudrin LG, Baulande S, Nicolas A, Champenois G, Meseure D, Vincent-Salomon A, Tardivon A, Laas E, Soumelis V, Colonna M, Mechta-Grigoriou F, Amigorena S, Romano E. Timperi E, et al. Among authors: molgora m. Cancer Res. 2022 Sep 16;82(18):3291-3306. doi: 10.1158/0008-5472.CAN-22-1427. Cancer Res. 2022. PMID: 35862581
43 results