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Superacid-Synthesized Fluorinated Diamines Act as Selective hCA IV Inhibitors.
Berrino E, Michelet B, Vitse K, Nocentini A, Bartolucci G, Martin-Mingot A, Gratteri P, Carta F, Supuran CT, Thibaudeau S. Berrino E, et al. Among authors: supuran ct. J Med Chem. 2024 Nov 14;67(21):19460-19474. doi: 10.1021/acs.jmedchem.4c01795. Epub 2024 Oct 24. J Med Chem. 2024. PMID: 39447020
Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.
Smaine FZ, Pacchiano F, Rami M, Barragan-Montero V, Vullo D, Scozzafava A, Winum JY, Supuran CT. Smaine FZ, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. doi: 10.1016/j.bmcl.2008.10.093. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18990571
2,081 results