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Super-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and Survival.
Yu J, Zhang Z, Chen Y, Wang J, Li G, Tao Y, Zhang Y, Yang Y, Zhang C, Li T, Cheng J, Ji T, Wei Z, Wang W, Fang F, Jiang W, Chu P, Yin H, Wu D, Li X, Wang X, Fan JJ, Hu S, Zhu ZH, Wu S, Lu J, Pan J. Yu J, et al. Adv Sci (Weinh). 2024 Oct 25:e2407113. doi: 10.1002/advs.202407113. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39454110
CEBPG promotes acute myeloid leukemia progression by enhancing EIF4EBP1.
Jiang Y, Wu SY, Chen YL, Zhang ZM, Tao YF, Xie Y, Liao XM, Li XL, Li G, Wu D, Wang HR, Zuo R, Cao HB, Pan JJ, Yu JJ, Jia SQ, Zhang Z, Chu XR, Zhang YP, Feng CX, Wang JW, Hu SY, Li ZH, Pan J, Fang F, Lu J. Jiang Y, et al. Among authors: yu jj. Cancer Cell Int. 2021 Nov 7;21(1):598. doi: 10.1186/s12935-021-02305-z. Cancer Cell Int. 2021. PMID: 34743716 Free PMC article.
BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma.
Chen YL, Li XL, Li G, Tao YF, Zhuo R, Cao HB, Jiao WY, Li ZH, Zhu ZH, Fang F, Xie Y, Liao XM, Wu D, Wang HR, Yu JJ, Jia SQ, Yang Y, Feng CX, Yang PC, Fei XD, Wang JW, Xu YY, Qian GH, Zhang ZM, Pan J. Chen YL, et al. Among authors: yu jj. Cell Biosci. 2022 Mar 18;12(1):33. doi: 10.1186/s13578-022-00769-8. Cell Biosci. 2022. PMID: 35303940 Free PMC article.
Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia.
Fang F, Lu J, Sang X, Tao YF, Wang JW, Zhang ZM, Zhang YP, Li XL, Xie Y, Wu SY, Chu XR, Li G, Wu D, Chen YL, Yu JJ, Jia SQ, Feng CX, Tian YY, Li ZH, Ling J, Hu SY, Pan J. Fang F, et al. Among authors: yu jj. J Exp Clin Cancer Res. 2022 Jul 16;41(1):225. doi: 10.1186/s13046-022-02428-9. J Exp Clin Cancer Res. 2022. PMID: 35842703 Free PMC article.
BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia.
Sang X, Zhang Y, Fang F, Gao L, Tao Y, Li X, Zhang Z, Wang J, Tian Y, Li Z, Yao D, Wu Y, Chu X, Zhang K, Ma L, Lu L, Chen Y, Yu J, Zhuo R, Wu S, Zhang Z, Pan J, Hu S. Sang X, et al. Among authors: yu j. J Immunol Res. 2022 Aug 1;2022:7912484. doi: 10.1155/2022/7912484. eCollection 2022. J Immunol Res. 2022. PMID: 35958877 Free PMC article.
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1.
Lu L, Wang J, Fang F, Guo A, Jiang S, Tao Y, Zhang Y, Li Y, Zhang K, Zhang Z, Zhuo R, Chu X, Li X, Tian Y, Ma L, Sang X, Chen Y, Yu J, Yang Y, Cao H, Gao J, Lu J, Hu S, Pan J, He H. Lu L, et al. Among authors: yu j. Cell Death Dis. 2023 Aug 12;14(8):518. doi: 10.1038/s41419-023-06039-w. Cell Death Dis. 2023. PMID: 37573405 Free PMC article.
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