Park KC - Search Results

1

Cancer stem cells: Masters of all traits.

Leck LYW, Abd El-Aziz YS, McKelvey KJ, Park KC, Sahni S, Lane DJR, Skoda J, Jansson PJ. Leck LYW, et al. Among authors: park kc. Biochim Biophys Acta Mol Basis Dis. 2024 Oct 23:167549. doi: 10.1016/j.bbadis.2024.167549. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 39454969 Review.

2

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.

Fang BA, Kovačević Ž, Park KC, Kalinowski DS, Jansson PJ, Lane DJ, Sahni S, Richardson DR. Fang BA, et al. Among authors: park kc. Biochim Biophys Acta. 2014 Jan;1845(1):1-19. doi: 10.1016/j.bbcan.2013.11.002. Epub 2013 Nov 21. Biochim Biophys Acta. 2014. PMID: 24269900 Review.

3

Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1.

Park KC, Menezes SV, Kalinowski DS, Sahni S, Jansson PJ, Kovacevic Z, Richardson DR. Park KC, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2644-2663. doi: 10.1016/j.bbadis.2018.04.011. Epub 2018 Apr 19. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29679718 Free article.

4

NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.

Sahni S, Gillson J, Park KC, Chiang S, Leck LYW, Jansson PJ, Richardson DR. Sahni S, et al. Among authors: park kc. Biochim Biophys Acta Gen Subj. 2020 Aug;1864(8):129625. doi: 10.1016/j.bbagen.2020.129625. Epub 2020 Apr 23. Biochim Biophys Acta Gen Subj. 2020. PMID: 32335136

5

Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.

Sahni S, Park KC, Kovacevic Z, Richardson DR. Sahni S, et al. Among authors: park kc. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1361-1378. doi: 10.1016/j.bbadis.2019.02.008. Epub 2019 Feb 11. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30763642 Free article.

6

Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones.

Al-Akra L, Bae DH, Sahni S, Huang MLH, Park KC, Lane DJR, Jansson PJ, Richardson DR. Al-Akra L, et al. Among authors: park kc. J Biol Chem. 2018 Mar 9;293(10):3562-3587. doi: 10.1074/jbc.M116.772699. Epub 2018 Jan 5. J Biol Chem. 2018. PMID: 29305422 Free PMC article.

7

Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.

Geleta B, Park KC, Jansson PJ, Sahni S, Maleki S, Xu Z, Murakami T, Pajic M, Apte MV, Richardson DR, Kovacevic Z. Geleta B, et al. Among authors: park kc. FASEB J. 2021 Feb;35(2):e21347. doi: 10.1096/fj.202002279R. FASEB J. 2021. PMID: 33484481

8

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.

Park KC, Fouani L, Jansson PJ, Wooi D, Sahni S, Lane DJ, Palanimuthu D, Lok HC, Kovačević Z, Huang ML, Kalinowski DS, Richardson DR. Park KC, et al. Metallomics. 2016 Sep 1;8(9):874-86. doi: 10.1039/c6mt00105j. Epub 2016 Jun 23. Metallomics. 2016. PMID: 27334916 Review.

9

Overcoming tamoxifen resistance in oestrogen receptor-positive breast cancer using the novel thiosemicarbazone anti-cancer agent, DpC.

Maqbool SN, Lim SC, Park KC, Hanif R, Richardson DR, Jansson PJ, Kovacevic Z. Maqbool SN, et al. Among authors: park kc. Br J Pharmacol. 2020 May;177(10):2365-2380. doi: 10.1111/bph.14985. Epub 2020 Feb 12. Br J Pharmacol. 2020. PMID: 31975484 Free PMC article.

10

Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.

Park KC, Geleta B, Leck LYW, Paluncic J, Chiang S, Jansson PJ, Kovacevic Z, Richardson DR. Park KC, et al. J Biol Chem. 2020 Jan 10;295(2):481-503. doi: 10.1074/jbc.RA119.011341. Epub 2019 Nov 19. J Biol Chem. 2020. PMID: 31744884 Free PMC article.

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