Cichero E - Search Results

1

Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays.

Piacente F, Guccione G, Scarano N, Lunaccio D, Miro C, Abbotto E, Salis A, Tasso B, Dentice M, Bruzzone S, Cichero E, Millo E. Piacente F, et al. Among authors: cichero e. Int J Mol Sci. 2024 Oct 15;25(20):11084. doi: 10.3390/ijms252011084. Int J Mol Sci. 2024. PMID: 39456864 Free PMC article.

2

Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands.

Scarano N, Espinoza S, Brullo C, Cichero E. Scarano N, et al. Among authors: cichero e. Int J Mol Sci. 2024 Jul 27;25(15):8226. doi: 10.3390/ijms25158226. Int J Mol Sci. 2024. PMID: 39125796 Free PMC article. Review.

3

Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective.

Scarano N, Brullo C, Musumeci F, Millo E, Bruzzone S, Schenone S, Cichero E. Scarano N, et al. Among authors: cichero e. Pharmaceuticals (Basel). 2024 May 8;17(5):601. doi: 10.3390/ph17050601. Pharmaceuticals (Basel). 2024. PMID: 38794171 Free PMC article. Review.

4

Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling.

Grossi G, Scarano N, Musumeci F, Tonelli M, Kanov E, Carbone A, Fossa P, Gainetdinov RR, Cichero E, Schenone S. Grossi G, et al. Among authors: cichero e. Molecules. 2024 Apr 11;29(8):1739. doi: 10.3390/molecules29081739. Molecules. 2024. PMID: 38675561 Free PMC article.

5

New Pyrazolyl Thioureas Active against the Staphylococcus Genus.

Schito AM, Caviglia D, Penco S, Spallarossa A, Cichero E, Tasso B, Brullo C. Schito AM, et al. Among authors: cichero e. Pharmaceuticals (Basel). 2024 Mar 15;17(3):376. doi: 10.3390/ph17030376. Pharmaceuticals (Basel). 2024. PMID: 38543162 Free PMC article.

6

New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists.

Scarano N, Di Palma F, Origlia N, Musumeci F, Schenone S, Spinelli S, Passalacqua M, Zocchi E, Sturla L, Cichero E, Cavalli A. Scarano N, et al. Among authors: cichero e. Pharmaceutics. 2023 Dec 12;15(12):2754. doi: 10.3390/pharmaceutics15122754. Pharmaceutics. 2023. PMID: 38140095 Free PMC article.

7

In Silico and In Vitro Evaluation of the Mechanism of Action of Three VX809-Based Hybrid Derivatives as Correctors of the F508del CFTR Protein.

Baroni D, Scarano N, Ludovico A, Brandas C, Parodi A, Lunaccio D, Fossa P, Moran O, Cichero E, Millo E. Baroni D, et al. Among authors: cichero e. Pharmaceuticals (Basel). 2023 Dec 8;16(12):1702. doi: 10.3390/ph16121702. Pharmaceuticals (Basel). 2023. PMID: 38139828 Free PMC article.

8

Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del-CFTR.

Spallarossa A, Pedemonte N, Pesce E, Millo E, Cichero E, Rosano C, Lusardi M, Iervasi E, Ponassi M. Spallarossa A, et al. Among authors: cichero e. ChemMedChem. 2024 Feb 16;19(4):e202300391. doi: 10.1002/cmdc.202300391. Epub 2024 Jan 16. ChemMedChem. 2024. PMID: 38105411

9

Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays.

Cichero E, Francesconi V, Casini B, Casale M, Kanov E, Gerasimov AS, Sukhanov I, Savchenko A, Espinoza S, Gainetdinov RR, Tonelli M. Cichero E, et al. Pharmaceuticals (Basel). 2023 Nov 20;16(11):1632. doi: 10.3390/ph16111632. Pharmaceuticals (Basel). 2023. PMID: 38004497 Free PMC article.

10

Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays.

Abbotto E, Casini B, Piacente F, Scarano N, Cerri E, Tonelli M, Astigiano C, Millo E, Sturla L, Bruzzone S, Cichero E. Abbotto E, et al. Among authors: cichero e. Pharmaceuticals (Basel). 2023 Sep 18;16(9):1316. doi: 10.3390/ph16091316. Pharmaceuticals (Basel). 2023. PMID: 37765125 Free PMC article.

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