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Page 1
High protection and transmission-blocking immunity elicited by single-cycle SARS-CoV-2 vaccine in hamsters.
Lett MJ, Otte F, Hauser D, Schön J, Kipfer ET, Hoffmann D, Halwe NJ, Breithaupt A, Ulrich L, Britzke T, Kochmann J, Corleis B, Zhang Y, Urda L, Cmiljanovic V, Lang C, Beer M, Mittelholzer C, Klimkait T. Lett MJ, et al. Among authors: breithaupt a. NPJ Vaccines. 2024 Oct 30;9(1):206. doi: 10.1038/s41541-024-00992-z. NPJ Vaccines. 2024. PMID: 39472701 Free PMC article.
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Hoffmann D, Corleis B, Rauch S, Roth N, Mühe J, Halwe NJ, Ulrich L, Fricke C, Schön J, Kraft A, Breithaupt A, Wernike K, Michelitsch A, Sick F, Wylezich C, Hoffmann B, Thran M, Thess A, Mueller SO, Mettenleiter TC, Petsch B, Dorhoi A, Beer M. Hoffmann D, et al. Among authors: breithaupt a. Nat Commun. 2021 Jun 30;12(1):4048. doi: 10.1038/s41467-021-24339-7. Nat Commun. 2021. PMID: 34193869 Free PMC article.
A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications.
Schön J, Barut GT, Trüeb BS, Halwe NJ, Berenguer Veiga I, Kratzel A, Ulrich L, Kelly JN, Brügger M, Wylezich C, Taddeo A, Aguiar Moreira E, Túrós D, Grau-Roma L, Ahrens AK, Schlottau K, Britzke T, Breithaupt A, Corleis B, Kochmann J, Oliveira Esteves BI, Almeida L, Thomann L, Devisme C, Stalder H, Steiner S, Ochsenbein S, Schmied K, Labroussaa F, Jores J, V'kovski P, Cmiljanovic V, Alves MP, Benarafa C, Ebert N, Hoffmann D, Beer M, Thiel V. Schön J, et al. Among authors: breithaupt a. Nat Microbiol. 2024 Aug;9(8):2099-2112. doi: 10.1038/s41564-024-01755-1. Epub 2024 Jul 12. Nat Microbiol. 2024. PMID: 38997518 Free PMC article.
SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.
Schlottau K, Rissmann M, Graaf A, Schön J, Sehl J, Wylezich C, Höper D, Mettenleiter TC, Balkema-Buschmann A, Harder T, Grund C, Hoffmann D, Breithaupt A, Beer M. Schlottau K, et al. Among authors: breithaupt a. Lancet Microbe. 2020 Sep;1(5):e218-e225. doi: 10.1016/S2666-5247(20)30089-6. Epub 2020 Jul 7. Lancet Microbe. 2020. PMID: 32838346 Free PMC article.
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta.
Ulrich L, Halwe NJ, Taddeo A, Ebert N, Schön J, Devisme C, Trüeb BS, Hoffmann B, Wider M, Fan X, Bekliz M, Essaidi-Laziosi M, Schmidt ML, Niemeyer D, Corman VM, Kraft A, Godel A, Laloli L, Kelly JN, Calderon BM, Breithaupt A, Wylezich C, Berenguer Veiga I, Gultom M, Osman S, Zhou B, Adea K, Meyer B, Eberhardt CS, Thomann L, Gsell M, Labroussaa F, Jores J, Summerfield A, Drosten C, Eckerle IA, Wentworth DE, Dijkman R, Hoffmann D, Thiel V, Beer M, Benarafa C. Ulrich L, et al. Among authors: breithaupt a. Nature. 2022 Feb;602(7896):307-313. doi: 10.1038/s41586-021-04342-0. Epub 2021 Dec 22. Nature. 2022. PMID: 34937050 Free PMC article.
Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets.
Graaf-Rau A, Schmies K, Breithaupt A, Ciminski K, Zimmer G, Summerfield A, Sehl-Ewert J, Lillie-Jaschniski K, Helmer C, Bielenberg W, Grosse Beilage E, Schwemmle M, Beer M, Harder T. Graaf-Rau A, et al. Among authors: breithaupt a. NPJ Vaccines. 2024 Jul 13;9(1):127. doi: 10.1038/s41541-024-00916-x. NPJ Vaccines. 2024. PMID: 39003272 Free PMC article.
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. Barut GT, et al. Among authors: breithaupt a. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. Nat Commun. 2022. PMID: 36207334 Free PMC article.
Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Dos Reis VP, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel D, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. Among authors: breithaupt a. bioRxiv [Preprint]. 2024 Aug 9:2024.08.09.607272. doi: 10.1101/2024.08.09.607272. bioRxiv. 2024. PMID: 39149352 Free PMC article. Preprint.
H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Pinho Dos Reis V, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel D, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. Among authors: breithaupt a. Nature. 2024 Sep 25. doi: 10.1038/s41586-024-08063-y. Online ahead of print. Nature. 2024. PMID: 39321846
Egyptian Fruit Bats (Rousettus aegyptiacus) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus.
Halwe NJ, Gorka M, Hoffmann B, Rissmann M, Breithaupt A, Schwemmle M, Beer M, Kandeil A, Ali MA, Kayali G, Hoffmann D, Balkema-Buschmann A. Halwe NJ, et al. Among authors: breithaupt a. Viruses. 2021 Apr 14;13(4):672. doi: 10.3390/v13040672. Viruses. 2021. PMID: 33919890 Free PMC article.
112 results