Wang C - Search Results

1

H₂S-releasing oridonin derivatives with improved antitumor activity by inhibiting the PI3K/AKT pathway.

Li H, Ma Q, Jia Y, Wang C, Wu J, Wang S, Hua H, Lu J, Li D. Li H, et al. Among authors: wang c, wang s. Bioorg Med Chem. 2024 Dec 1;115:117968. doi: 10.1016/j.bmc.2024.117968. Epub 2024 Oct 28. Bioorg Med Chem. 2024. PMID: 39481184

2

Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia.

Xiang Q, Wu T, Zhang C, Wang C, Xu H, Hu Q, Hu J, Luo G, Zhuang X, Wu X, Zhang Y, Xu Y. Xiang Q, et al. Among authors: wang c. Bioorg Chem. 2024 Jan;142:106950. doi: 10.1016/j.bioorg.2023.106950. Epub 2023 Oct 30. Bioorg Chem. 2024. PMID: 37924753

3

Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach.

Qin S, Feng L, Zhao Q, Yan Z, Lyu X, Li K, Mu B, Chen Y, Lu W, Wang C, Suo Y, Yue J, Cui M, Li Y, Zhao Y, Duan Z, Zhu J, Lu X. Qin S, et al. Among authors: wang c. J Med Chem. 2024 Jan 25;67(2):1079-1092. doi: 10.1021/acs.jmedchem.3c01463. Epub 2024 Jan 3. J Med Chem. 2024. PMID: 38166388

4

Design and synthesis of 6,20-epoxy A-ring modified oridonin derivatives with antitumor activity through extrinsic and mitochondrial pathways.

Li H, Luo X, Zhu F, Wang C, Wang J, Wang S, Hua H, Lu J, Li D. Li H, et al. Among authors: wang j, wang c, wang s. Bioorg Chem. 2024 Oct;151:107632. doi: 10.1016/j.bioorg.2024.107632. Epub 2024 Jul 11. Bioorg Chem. 2024. PMID: 39003943

5

Design, synthesis, and analgesia evaluation of novel Transient Receptor Potential Vanilloid 1 (TRPV1) agonists modified from Cannabidiol (CBD).

Jin F, Wen Y, Lin G, Yu S, Wang C, Ye W, Zhang J. Jin F, et al. Among authors: wang c. Bioorg Med Chem. 2023 Jul 15;90:117379. doi: 10.1016/j.bmc.2023.117379. Epub 2023 Jun 13. Bioorg Med Chem. 2023. PMID: 37336082

6

Phytochemical investigation of Asarum sieboldii var. seoulense and the phenotypic profiles of its constituents against a Parkinson's Disease olfactory cell line.

Wang C, Nguyen T, Yang X, Mellick GD, Feng Y. Wang C, et al. Bioorg Med Chem Lett. 2023 Aug 15;92:129386. doi: 10.1016/j.bmcl.2023.129386. Epub 2023 Jun 22. Bioorg Med Chem Lett. 2023. PMID: 37355024 Free article.

7

Design of MERS-CoV entry inhibitory short peptides based on helix-stabilizing strategies.

Li J, Li Q, Xia S, Tu J, Zheng L, Wang Q, Jiang S, Wang C. Li J, et al. Among authors: wang c, wang q. Bioorg Med Chem Lett. 2024 Jan 1;97:129569. doi: 10.1016/j.bmcl.2023.129569. Epub 2023 Nov 24. Bioorg Med Chem Lett. 2024. PMID: 38008340

8

Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.

Wang Y, Wang C, Liu T, Qi H, Chen S, Cai X, Zhang M, Aliper A, Ren F, Ding X, Zhavoronkov A. Wang Y, et al. Among authors: wang c. J Med Chem. 2024 Jan 11;67(1):420-432. doi: 10.1021/acs.jmedchem.3c01476. Epub 2023 Dec 26. J Med Chem. 2024. PMID: 38146659

9

Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities.

Wang C, Zhang Y, Yang S, Shi L, Rong R, Zhang T, Wu Y, Xing D. Wang C, et al. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2302320. doi: 10.1080/14756366.2024.2302320. Epub 2024 Jan 14. J Enzyme Inhib Med Chem. 2024. PMID: 38221788 Free PMC article.

10

Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors.

Wang Y, Wang C, Liu J, Sun D, Meng F, Zhang M, Aliper A, Ren F, Zhavoronkov A, Ding X. Wang Y, et al. Among authors: wang c. Bioorg Med Chem. 2024 Apr 1;103:117662. doi: 10.1016/j.bmc.2024.117662. Epub 2024 Mar 6. Bioorg Med Chem. 2024. PMID: 38493730

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